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Pyrimethamine / Sulfadoxine
Known as:
PYRIMETHAMINE/SULFADOXINE
, sulphadoxine-pyrimethamine
, fanasil, pyrimethamine drug combination
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A combination product containing pyrimethamine and sulfadoxine. Pyrimethamine is a competitive inhibitor of dihydrofolate reductase (DHFR). DHFR is a…
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National Institutes of Health
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Related topics
Related topics
5 relations
Broader (2)
Antimalarials
Drug Combinations
Pyrimethamine
Sulfadoxine
Narrower (1)
Suldox
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Changes in health workers' malaria diagnosis and treatment practices in Kenya
E. Juma
,
D. Zurovac
Malaria Journal
2011
Corpus ID: 5619405
BackgroundChange of Kenyan treatment policy for uncomplicated malaria from sulphadoxine-pyrimethamine to artemether-lumefantrine…
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Review
2006
Review
2006
Drugs for preventing malaria in pregnant women.
P. Garner
,
A. M. Gülmezoglu
Cochrane Database of Systematic Reviews
2006
Corpus ID: 2426817
BACKGROUND Malaria contributes to maternal illness and anaemia in pregnancy, especially in first-time mothers, and can harm the…
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Review
2004
Review
2004
The origins of antimalarial drug resistance.
I. Hastings
Trends in Parasitology
2004
Corpus ID: 32910780
Review
2002
Review
2002
The evolution of drug-resistant malaria: the role of drug elimination half-life.
I. Hastings
,
W. Watkins
,
N. White
Philosophical transactions of the Royal Society…
2002
Corpus ID: 25444436
This paper seeks to define and quantify the influence of drug elimination half-life on the evolution of antimalarial drug…
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Review
2002
Review
2002
Integrated Approach to Malaria Control
C. Shiff
Clinical Microbiology Reviews
2002
Corpus ID: 24986152
SUMMARY Malaria draws global attention in a cyclic manner, with interest and associated financing waxing and waning according to…
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Highly Cited
1999
Highly Cited
1999
Averting a malaria disaster
N. White
,
F. Nosten
,
+15 authors
P. Olliaro
The Lancet
1999
Corpus ID: 25279819
Highly Cited
1999
Highly Cited
1999
Increased prevalence of malaria in HIV‐infected pregnant women and its implications for malaria control
F. Verhoeff
,
B. Brabin
,
C. Hart
,
L. Chimsuku
,
P. Kazembe
,
R. Broadhead
Tropical medicine & international health
1999
Corpus ID: 24628645
Summary objectives To examine in pregnant women the relationship between HIV infection and malaria prevalence and to determine…
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Highly Cited
1998
Highly Cited
1998
Cycloguanil and its parent compound proguanil demonstrate distinct activities against Plasmodium falciparum malaria parasites transformed with human dihydrofolate reductase.
D. Fidock
,
T. Nomura
,
T. Wellems
Molecular Pharmacology
1998
Corpus ID: 10115046
The lack of suitable antimalarial agents to replace chloroquine and pyrimethamine/sulfadoxine threatens efforts to control the…
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Review
1994
Review
1994
Epidemiology of drug resistance in malaria.
W. Wernsdorfer
,
W. Wernsdorfer
Acta Tropica
1994
Corpus ID: 7611742
Highly Cited
1992
Highly Cited
1992
Effect of iron chelation therapy on recovery from deep coma in children with cerebral malaria.
V. Gordeuk
,
P. Thuma
,
+10 authors
A. Poltera
New England Journal of Medicine
1992
Corpus ID: 12992254
BACKGROUND Cerebral malaria is a severe complication of Plasmodium falciparum infection in children, with a mortality rate of 15…
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