Drug Combinations

Known as: Combinations, Drug, combination drug, drug combination 
Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1950-2017
020040019502016

Papers overview

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Highly Cited
2015
Highly Cited
2015
Reversal of HIV-1 latency by small molecules is a potential cure strategy. This approach will likely require effective drug… (More)
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Highly Cited
2014
Highly Cited
2014
Targeted cancer therapies have produced substantial clinical responses, but most tumors develop resistance to these drugs. Here… (More)
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Highly Cited
2010
Highly Cited
2010
This brief perspective article focuses on the most common errors and pitfalls, as well as the do's and don'ts in drug combination… (More)
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Highly Cited
2010
Highly Cited
2010
Targeted therapeutics hold tremendous promise in inhibiting cancer cell proliferation. However, targeting proteins individually… (More)
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Highly Cited
2009
Highly Cited
2009
Drug combinations are a promising strategy to overcome the compensatory mechanisms and unwanted off-target effects that limit the… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Compliance with treatment is a sine qua non for successful treatment of chronic conditions like hypertension. Fixed… (More)
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Highly Cited
2006
Highly Cited
2006
BMS-354825 (dasatinib) and AMN107 (nilotinib) are potent alternate Abl inhibitors with activity against many imatinib mesylate… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Trastuzumab, a humanized anti-HER2 antibody, increases the clinical benefit of first-line chemotherapy in patients… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Ewing's sarcoma and primitive neuroectodermal tumor of bone are closely related, highly malignant tumors of children… (More)
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Highly Cited
1997
Highly Cited
1997
In evaluating current combination drug regimens for treatment of human immunodeficiency virus (HIV) disease, it is important to… (More)
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