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Drug Combinations

Known as: Combinations, Drug, combination drug, drug combination 
Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Combination therapies exploit the chances for better efficacy, decreased toxicity, and reduced development of drug resistance and… 
Highly Cited
2014
Highly Cited
2014
Targeted cancer therapies have produced substantial clinical responses, but most tumors develop resistance to these drugs. Here… 
Highly Cited
2010
Highly Cited
2010
  • T. Chou
  • Cancer research
  • 2010
  • Corpus ID: 1324495
This brief perspective article focuses on the most common errors and pitfalls, as well as the do's and don'ts in drug combination… 
Review
2010
Review
2010
Two or more antihypertensive agents are increasingly used to control blood pressure (BP) in hypertensive patients. However, it is… 
Highly Cited
2009
Highly Cited
2009
Drug combinations are a promising strategy to overcome the compensatory mechanisms and unwanted off-target effects that limit the… 
Review
2006
Review
2006
  • T. Chou
  • Pharmacological Reviews
  • 2006
  • Corpus ID: 7055257
The median-effect equation derived from the mass-action law principle at equilibrium-steady state via mathematical induction and… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND Trastuzumab, a humanized anti-HER2 antibody, increases the clinical benefit of first-line chemotherapy in patients… 
Highly Cited
1997
Highly Cited
1997
In evaluating current combination drug regimens for treatment of human immunodeficiency virus (HIV) disease, it is important to… 
Highly Cited
1992
Highly Cited
1992
BACKGROUND The combination of streptozocin and fluorouracil has become the standard therapy for advanced islet-cell carcinoma…