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Pyrimethamine

Known as: 5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine, CD, Primethamine 
A synthetic derivative of ethyl-pyrimidine with potent antimalarial properties. Pyrimethamine is a competitive inhibitor of dihydrofolate reductase… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (19)

3-azidopyrimethamineCC 83ChloridinChloridine
AIDS-Related Opportunistic InfectionsAnemia, PerniciousDapsone / PyrimethamineDrug Allergy

Broader (5)

AntimalarialsAntiprotozoal AgentsFolic Acid AntagonistsPyrimidine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1996
1996
Cadmium influx across isolated Carcinus gill epithelium interaction of lanthanum and calcium with cadmium influxes
The effects of Ca and La on Cd transport across apical and basolateral gill surfaces were examined in isolated perfused Carcinus… 
1995
1995
EFFECT OF CADMIUM STRESS ON GROWTH AND PHOTO- SYNTHESIS OF YOUNG BARLEY (H. vulgare L.) PLANTS. 2. STRUCTURAL AND FUNCTIONAL CHANGES IN THE PHOTOSYNTHETIC APPARATUS
Summary. The influence of Cd-stress on the structure and functional activity of the photosynthetic apparatus of 15-day-old barley… 
1984
1984
Hemodialysis elimination rates and clearance of gentamicin and tobramycin
The apparent hemodialyzer elimination rate constant and clearance for gentamicin and tobramycin were determined during 100… 
1983
1983
Uptake of heavy metals by crops in relation to their concentration in the soil solution
SummaryOf 20 Dutch soils, concentrations in the soil solution and total contents of Zn, Cd, Pb and Cu were determined. In… 
Highly Cited
1981
Highly Cited
1981
Cadmium in man measured in vivo by x-ray fluorescence analysis.
The sensitivity and detection limit for measurements of the concentration of cadmium in the kidney cortex of man in vivo have… 
Highly Cited
1980
Highly Cited
1980
Pyrimethamine sensitivity in Plasmodium falciparum: determination in vitro by a modified 48-hour test.
Four strains of Plasmodium falciparum recently isolated in culture were assessed in vitro for their response to pyrimethamine. A… 
Highly Cited
1979
Highly Cited
1979
Studies on Plasmodium falciparum in continuous cultivation. I. The effect of chloroquine and pyrimethamine on parasite growth and viability.
Recent advances in the in vitro study of human malaria have provided the knowledge to maintain Plasmodium falciparum in… 
1974
1974
Combined effects of cadmium and salinity on development and survival of herring eggs
KurzfassungEier des herbstlaichenden Ostseeherings (Clupea harengus L.) wurden in natürlichem und in Cadmium kontaminiertem… 
Highly Cited
1969
Highly Cited
1969
Mechanism of pyrimethamine-induced megaloblastosis in human bone marrow.
Abstract Megaloblastosis appeared in a patient receiving pyrimethamine. Pyrimethamine seemed to act as does the folate antagonist… 
Review
1955
Review
1955
The mode of action of sulphonamides, proguanil and pyrimethamine on Plasmodium gallinaceum.
Despite the mass of information on the antimalarial action of sulphonamides, proguanil, and pyrimethamine (see Goodwin and Rollo… 
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