Skip to search formSkip to main contentSkip to account menu

Pyrimethamine

Known as: 5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine, CD, Primethamine 
A synthetic derivative of ethyl-pyrimidine with potent antimalarial properties. Pyrimethamine is a competitive inhibitor of dihydrofolate reductase… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (19)

3-azidopyrimethamineCC 83ChloridinChloridine
AIDS-Related Opportunistic InfectionsAnemia, PerniciousDapsone / PyrimethamineDrug Allergy

Broader (5)

AntimalarialsAntiprotozoal AgentsFolic Acid AntagonistsPyrimidine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Gastrointestinal uptake and fate of cadmium in rainbow trout acclimated to sublethal dietary cadmium.
Highly Cited
2004
Highly Cited
2004
Cadmium concentration in vegetable crops grown in a sandy soil as affected by Cd levels in fertilizer and soil pH
Field trials were conducted over a three-year period with chinese cabbage (Brassica pekinensis Rupr.) and carrots (Daucus carota… 
Highly Cited
2003
Highly Cited
2003
Environmental cadmium levels increase phytochelatin and glutathione in lettuce grown in a chelator-buffered nutrient solution.
Phytochelatins are enzymatically synthesized peptides involved in metal detoxification and have been measured in plants grown at… 
Highly Cited
2002
Highly Cited
2002
Kinetic uptake of bioavailable cadmium, selenium, and zinc by Daphnia magna
Kinetic uptake of Cd, Se(IV), and Zn by Daphnia magna from the dissolved phase was determined using radiotracer techniques in… 
Highly Cited
1995
Highly Cited
1995
A mutation-specific PCR system to detect sequence variation in the dihydropteroate synthetase gene of Plasmodium falciparum.
Review
1993
Review
1993
The detection and assessment of the aneugenic potential of environmental chemicals: the European Community Aneuploidy Project.
Highly Cited
1991
Highly Cited
1991
Cysteine, gamma-Glutamylcysteine, and Glutathione Levels in Maize Seedlings : Distribution and Translocation in Normal and Cadmium-Exposed Plants.
The levels of cysteine (Cys), gamma-glutamylcysteine (gammaEC), and glutathione (GSH) were measured in the endosperms, scutella… 
Highly Cited
1989
Highly Cited
1989
Poly(gamma-glutamylcysteinyl)glycine Synthesis in Datura innoxia and Binding with Cadmium : Role in Cadmium Tolerance.
The effects of Cd on poly(gamma-glutamylcysteinyl)glycine [(gammaEC)(n)G] biosynthesis and formation of (gammaEC)(n)G:Cd… 
Highly Cited
1970
Highly Cited
1970
Effects of divalent metal ions on chlorophyll a fluorescence in isolated spinach chloroplasts.
Highly Cited
1965
Highly Cited
1965
Drug resistance in Plasmodium berghei Vincke and Lips, 1948. 3. Multiple drug resistance.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)