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In 2010 there were more than 200 million cases of malaria, and at least 655,000 deaths. The World Health Organization has… Expand Malaria is a devastating infection caused by protozoa of the genus Plasmodium. Drug resistance is widespread, no new chemical… Expand Background: Antimalarial drugs (AMs), chloroquine (CQ) and hydroxychloroquine (HCQ), are frequently withdrawn in patients with… Expand Malaria is a global health problem that threatens 300–500 million people and kills more than one million people annually. Disease… Expand Malaria, the most prevalent and most pernicious parasitic disease of humans, is estimated to kill between one and two million… Expand Increased efforts in antimalarial drug discovery are urgently needed. The goal must be to develop safe and affordable new drugs… Expand Continued and sustainable improvements in antimalarial medicines through focused research and development are essential for the… Expand Throughout the latter half of this century, the development and spread of resistance to most front-line antimalarial compounds… Expand A mevalonate-independent pathway of isoprenoid biosynthesis present in Plasmodium falciparum was shown to represent an effective… Expand A rapid, semiautomated microdilution method was developed for measuring the activity of potential antimalarial drugs against… Expand