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Antimalarials

Known as: Antimalarial Drugs, Antimalarial Agent [TC], Antimalarial Agents 
Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life… 
National Institutes of Health

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AcedapsoneAtovaquone 250 MG / proguanil hydrochloride 100 MG Oral TabletBRL 6231Chloroquine
Chloroquine hydrochlorideIn BloodMalariaPlasmodium <genus>

Papers overview

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Highly Cited
2011
Highly Cited
2011
Mechanism of Endosomal TLR Inhibition by Antimalarial Drugs and Imidazoquinolines
Endosomal TLRs play an important role in innate immune response as well as in autoimmune processes. In the therapy of systemic… 
Highly Cited
2004
Highly Cited
2004
Identification of an antimalarial synthetic trioxolane drug development candidate
The discovery of artemisinin more than 30 years ago provided a completely new antimalarial structural prototype; that is, a… 
Review
2004
Review
2004
Antimalarial Drug Toxicity
Malaria, caused mostly by Plasmodium falciparum and P. vivax, remains one of the most important infectious diseases in the world… 
Highly Cited
2001
Highly Cited
2001
Antimalarial Alkoxylated and Hydroxylated Chalones: Structure−Activity Relationship Analysis
Chalcones with 2‘,3‘,4‘-trimethoxy, 2‘,4‘-dimethoxy, 4‘-methoxy, 4‘-ethoxy, 2‘,4‘-dihydroxy, and 4‘-hydroxy groups on ring B were… 
Highly Cited
2000
Highly Cited
2000
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
Throughout the latter half of this century, the development and spread of resistance to most front-line antimalarial compounds… 
Highly Cited
1999
Highly Cited
1999
Averting a malaria disaster
Highly Cited
1997
Highly Cited
1997
Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue.
The antimalarial activities of ferrocenic compounds mimicking chloroquine and active upon chloroquine-resistant strains of… 
Review
1991
Review
1991
Molecular mechanisms of quinone cytotoxicity.
Highly Cited
1988
Highly Cited
1988
Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum.
We describe the isolation and the sequence of the gene for the bifunctional enzyme dihydrofolate reductase-thymidylate synthase… 
Highly Cited
1976
Highly Cited
1976
The importance of phospholipase-A2 in prostaglandin biosynthesis.
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