Skip to search formSkip to main contentSkip to account menu

Acedapsone

Known as: 4,4'-Diacetyldiaminodiphenylsulfone, Sulfadiamine, 4',4'''-Sulfonylbis(acetanilide) 
Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (3)

Anti-Infective AgentsAntimalarialsLeprostatic Agents

Narrower (2)

HansolarRodilone
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Activation of diacetyldapsone and a preliminary evaluation of a cyclodextrin–diacetyldapsone complex in cultured lung cells
A diacetyldapsone–2‐hydroxypropyl‐β‐cyclodextrin complex (DADDS–CD) was evaluated with regard to the ability of cultured lung… 
1996
1996
Effectiveness of MDT in multibacillary leprosy.
The study on the use of World Health Organization multidrug therapy (WHO/MDT) under field conditions was initiated in December… 
1983
1983
A rabbit--in vitro system to evaluate drug action against Plasmodium falciparum.
1976
1976
Susceptibility of Mycobacterium leprae to Dapsone as a Determinant of Patient Response to Acedapsone
In the course of a clinical trial of acedapsone therapy in 17 patients with lepromatous leprosy, the rate of response to therapy… 
1972
1972
Disposition of the Antileprosy Drug, Dapsone, in the Mouse 1
Summary The T 1/2 of DDS ranged from 2 to 4 hr in male and female BALB/c and in male B6C3F1 mice. It was independent of strain or… 
1971
1971
Treatment with 4,4'-diacetyldiaminodiphenylsulfone (DADDS) of leprosy patients in the Karimui, New Guinea.
1970
1970
Therapy of leprosy.
The latest developments and ideas in the therapy of leprosy are discussed, the need for long-term studies being stressed. The… 
1969
1969
Respository drugs. IV. 4',4'''-Sulfonylbisacetanilide (Acedapsone, DADDS) and related sulfanilylanilides with prolonged antimalarial and antileprotic action.
1968
1968
The therapeutic effect of 4,4'-diacetyldiamino-diphenylsulfone (DADDS) in leprosy.
Summary The repository sulfone 4,4′-diacetyldiaminodiphenylsulfone (DADDS) was studied for its efficacy in lepromatous leprosy… 
1965
1965
The repository antimalarial activities of 4,4'-diacetylaminodiphenylsulfone and cycloguanil pamoate (Cl-501) in monkeys relative to local release following parenteral administration.
Repository antimalarials were implanted subcutaneously in dialysis sacks for various intervals to control the periods of local… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)