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Acedapsone

Known as: 4,4'-Diacetyldiaminodiphenylsulfone, Sulfadiamine, 4',4'''-Sulfonylbis(acetanilide) 
Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (3)

Anti-Infective AgentsAntimalarialsLeprostatic Agents

Narrower (2)

HansolarRodilone
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Questionnaire Design to Determine Children's Thermal Sensation, Preference and Acceptability in the Classroom
School buildings integrate three significant aspects of sustainability research - building performance, energy consumption and… 
2004
2004
Individual differences in imagery and reports of aversions
Recent theoretical models highlighting the role of imagery in trauma and aversion learning focus on the role of images in memory… 
2003
2003
The Transition to School Project: Results from the classroom
Abstract Conduct problems in children are common, and are associated with significant costs to the family, schools, and society… 
1983
1983
A rabbit--in vitro system to evaluate drug action against Plasmodium falciparum.
1979
1979
The pharmacokinetics of dapsone and acetylated dapsone in serum and saliva.
The concentrations of dapsone (DDS) and its acetylated derivatives (MADDS and DADDS) were determined in the serum and saliva… 
1976
1976
Susceptibility of Mycobacterium leprae to Dapsone as a Determinant of Patient Response to Acedapsone
In the course of a clinical trial of acedapsone therapy in 17 patients with lepromatous leprosy, the rate of response to therapy… 
1972
1972
Disposition of the Antileprosy Drug, Dapsone, in the Mouse 1
Summary The T 1/2 of DDS ranged from 2 to 4 hr in male and female BALB/c and in male B6C3F1 mice. It was independent of strain or… 
1972
1972
The death rate of Mycobacterium leprae during treatment of lepromatous leprosy with acedapsone (DADDS).
Abstract Patients with previously untreated lepromatous leprosy were treated by injections of acedapsone (DADDS), a repository… 
1971
1971
Application of spectrophotofluorometric procedures to some problems in Mycobacterium leprae infections in mice and man treated with dapsone (DDS), diacetyl-DDS (DADDS), and di-formyl-DDS (DFD).
Abstract Recently described spectrophotofluorometric procedures for the determination of dapsone (DDS), which are sensitive to… 
1968
1968
The therapeutic effect of 4,4'-diacetyldiamino-diphenylsulfone (DADDS) in leprosy.
Summary The repository sulfone 4,4′-diacetyldiaminodiphenylsulfone (DADDS) was studied for its efficacy in lepromatous leprosy… 
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