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Acedapsone

Known as: 4,4'-Diacetyldiaminodiphenylsulfone, Sulfadiamine, 4',4'''-Sulfonylbis(acetanilide) 
Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (3)

Anti-Infective AgentsAntimalarialsLeprostatic Agents

Narrower (2)

HansolarRodilone
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
DEVELOPING PROFESSIONAL LEARNING IN K-BASED ECONOMY AND K-SOCIETY USING ACTION LEARNING AND ACTION RESEARCH APPROACHES
Following rapid economic and social advancement, Malaysia has placed a great emphasis on Information and Communication Technology… 
1986
1986
Blood dapsone levels in leprosy patients treated with acedapsone.
The metabolism of the repository drug acedapsone (DADDS,4,4'-diacetyldiaminodiphenyl sulfone) was studied in 15 individuals… 
1984
1984
Activities of respository preparations of cycloguanil pamoate and 4,4'-diacetyldiaminodiphenylsulfone, alone and in combination, against infections with Plasmodium cynomolgi in rhesus monkeys
The studies summarized in this report were concerned with the capacities of repository preparations of cycloguanil pamoate (CGT-P… 
1972
1972
Disposition of the Antileprosy Drug, Dapsone, in the Mouse 1
Summary The T 1/2 of DDS ranged from 2 to 4 hr in male and female BALB/c and in male B6C3F1 mice. It was independent of strain or… 
1972
1972
Acedapsone in leprosy treatment: trial in 68 active cases in Micronesia.
This report describes the response of 68 active cases of leprosy, treated with DADDS (4,4'-diacetyldiaminodiphenylsulfon e… 
1971
1971
Treatment with 4,4'-diacetyldiaminodiphenylsulfone (DADDS) of leprosy patients in the Karimui, New Guinea.
1970
1970
Therapy of leprosy.
The latest developments and ideas in the therapy of leprosy are discussed, the need for long-term studies being stressed. The… 
1969
1969
A fluorometric method for the simultaneous determination of 4,4'-diaminodiphenyl sulfone (DDS), N-acetyl-DDS (MADDS) and N,N'-diacetyl-DDS (DADDS) in serum or urine.
The demonstration th at the growth of M. Zep1'Oe is inhibited by ex tremely low concentrations of 4,4'-diaminodiphenyl sulfone… 
1968
1968
The therapeutic effect of 4,4'-diacetyldiamino-diphenylsulfone (DADDS) in leprosy.
Summary The repository sulfone 4,4′-diacetyldiaminodiphenylsulfone (DADDS) was studied for its efficacy in lepromatous leprosy… 
1965
1965
The repository antimalarial activities of 4,4'-diacetylaminodiphenylsulfone and cycloguanil pamoate (Cl-501) in monkeys relative to local release following parenteral administration.
Repository antimalarials were implanted subcutaneously in dialysis sacks for various intervals to control the periods of local… 
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