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Sulfadoxine

Known as: Sulfadoxine [Chemical/Ingredient], Sulfadoxinum, Sulphormetoxin 
A broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties. Sulfadoxine… 
National Institutes of Health

Related topics

Related topics

24 relations
Anemia, MegaloblasticDisorders of Porphyrin MetabolismDrug AllergyIn Blood

Broader (3)

Anti-Infective AgentsAnti-Infective Agents, UrinaryAntimalarials

Narrower (5)

FanasilN(4)-acetylsulfadoxinePyrimethamine / Sulfadoxinemefloquine-sulfadoxine-pyrimethamine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Fabrication of CoFe2O4-graphene nanocomposite and its application in the magnetic solid phase extraction of sulfonamides from milk samples.
Highly Cited
2013
Highly Cited
2013
Dispersive liquid-liquid microextraction combined with ultra-high performance liquid chromatography for the simultaneous determination of 25 sulfonamide and quinolone antibiotics in water samples.
Highly Cited
2009
Highly Cited
2009
A single LC-tandem mass spectrometry method for the simultaneous determination of 14 antimalarial drugs and their metabolites in human plasma.
Review
2007
Review
2007
Safety and Toxicity of Sulfadoxine/Pyrimethamine
Plasmodium falciparum infection during pregnancy is strongly associated with maternal anaemia and low birth weight, contributing… 
Highly Cited
2004
Highly Cited
2004
Quantitative analysis of twelve sulfonamides in honey after acidic hydrolysis by high-performance liquid chromatography with post-column derivatization and fluorescence detection.
Review
2004
Review
2004
Antimalarial Drug Toxicity
Malaria, caused mostly by Plasmodium falciparum and P. vivax, remains one of the most important infectious diseases in the world… 
Highly Cited
2000
Highly Cited
2000
Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum
The declining efficacy of chloroquine and pyrimethamine/sulphadoxine in the treatment of human malaria has led to the use of… 
Highly Cited
1997
Highly Cited
1997
Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization
Sulfadoxine/pyrimethamine (Fansidar) is widely used in Africa for treating chloroquine‐resistant falciparum malaria. To clarify… 
Highly Cited
1995
Highly Cited
1995
A mutation-specific PCR system to detect sequence variation in the dihydropteroate synthetase gene of Plasmodium falciparum.
Highly Cited
1984
Highly Cited
1984
Synergistic antimalarial activity of pyrimethamine and sulfadoxine against Plasmodium falciparum in vitro.
Two strains of Plasmodium falciparum were tested in vitro for sensitivity to the dihydrofolate reductase inhibitor pyrimethamine… 
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