Sulfadoxine

Known as: Sulfadoxine [Chemical/Ingredient], Sulfadoxinum, Sulphormetoxin 
A broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties. Sulfadoxine… (More)

Topic mentions per year

Topic mentions per year

1964-2018
05010019642018

Papers overview

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2010
2010
The Thailand-Cambodia border is the epicenter for drug-resistant falciparum malaria. Previous studies have shown that chloroquine… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND In the Sahel and sub-Sahelian regions of Africa, malaria transmission is highly seasonal. During a short period of… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE Our objective was to characterize the pharmacokinetic properties of sulfadoxine-pyrimethamine in African adults and… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND In 1993, Malawi became the first country in Africa to replace chloroquine with the combination of sulfadoxine and… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Many countries in Africa are considering a change to combination treatment for falciparum malaria because of the… (More)
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Highly Cited
2005
Highly Cited
2005
The emergence and spread of multidrug resistant Plasmodium falciparum has severely limited the therapeutic options for the… (More)
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Highly Cited
2002
Highly Cited
2002
Molecular assays for monitoring sulfadoxine-pyrimethamine-resistant Plasmodium falciparum have not been implemented because of… (More)
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Highly Cited
1998
Highly Cited
1998
A fever case management (CM) approach using sulfadoxine-pyrimethamine (SP) was compared with two presumptive intertmittent SP… (More)
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Highly Cited
1998
Highly Cited
1998
With the spread of resistance to chloroquine, the combination of sulphadoxine and pyrimethamine is growing in importance for the… (More)
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Highly Cited
1994
Highly Cited
1994
Dihydropteroate synthase (H2Pte synthase) is the target of the sulfur-based antimalarial drugs, which are frequently used in… (More)
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