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Prostaglandin H2

Known as: PGH2, Prosta-5,13-dien-1-oic acid, 9,11-epidioxy-15-hydroxy-, (5Z,9alpha,11alpha,13E,15S)-, PGH(2) 
A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific… 
National Institutes of Health

Related topics

Related topics

15 relations
In BloodPTGS2 genePTGS2 protein, humanPTGS2 wt Allele

Narrower (1)

prostaglandin H2 9-cyclic ether

Papers overview

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1986
1986
Production of steroids and release of prostaglandins by spherical pig blastocysts in vitro.
Levels of pregnenolone and progesterone in spherical pig blastocysts (near 4 and 15 microM respectively) exceeded respective… 
Highly Cited
1983
Highly Cited
1983
Platelet aggregation and exposure of fibrinogen receptors by prostaglandin endoperoxide analogues.
Two stable analogues of prostaglandin endoperoxides9.1 1 -azo-prostanoid III (9-1 1 -azo PGH2) and 9.1 1 -methanoepoxy PGH2… 
Highly Cited
1979
Highly Cited
1979
Blood platelets do not provide endoperoxides for vascular prostacyclin production
PROSTACYCLIN (PGI2), the most active natural inhibitor of blood platelet aggregation described so far, is synthesised from the… 
1979
1979
Responses of baboon cerebral and extracerebral arteries to prostacyclin and prostaglandin endoperoxide in vitro and in vivo.
The responses of baboon cerebral and extracerebral arteries to prostaglandin endoperoxide (PGH2) and prostacyclin (PGI2) were… 
1979
1979
The effects of prostaglandins on secretion of glucagon and insulin by the perfused rat pancreas.
The secretion of both glucagon and insulin by the isolated perfused rat pancreas was significantly stimulated by 10(-7) M PGH2… 
Highly Cited
1978
Highly Cited
1978
Actions of prostaglandins on isolated perfused cat coronary arteries.
Effects of prostaglandins on coronary arterial smooth muscle were studied in isolated perfused cat coronary arteries. This… 
Highly Cited
1977
Highly Cited
1977
Prostaglandin endoperoxides and thromboxane A2 can induce platelet aggregation in the absence of secretion
PLATELET aggregation and secretion are widely studied not only because they are believed to reflect the major in vivo platelet… 
Highly Cited
1976
Highly Cited
1976
A direct,stereocontrolled total synthesis of the 9,11-azo analogue of the prostaglandin endoperoxide, PGH2.
1976
1976
Clinical, functional and pathogenetic aspects of bronchial reactivity to prostaglandins F2alpha, E1, and E2.
Based on our results and on those reported in literature, we may draw the following conclusions. As a rule, asthmatic patients… 
1976
1976
Rat platelets aggregate in the absence of endogenous precursors of prostaglandin endoperoxides
THE prostaglandin (PG) endoperoxides, PGG2 and PGH2, are thought to have a function in human platelet aggregation, since they are…