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PTGS2 protein, human

Known as: PTGS2, Prostaglandin H2 Synthase 2, Cyclooxygenase 
An enzyme that speeds up the formation of substances that cause inflammation and pain. It may also cause tumor cells to grow. Some tumors have high… 
National Institutes of Health

Related topics

Related topics

17 relations
Cyclooxygenase 2 Ag:PrThr:Pt:Tiss:Ord:Immune stainEGF-Like DomainEndoplasmic ReticulumEnzyme Gene

Broader (1)

cyclooxygenase 2

Papers overview

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Highly Cited
2010
Highly Cited
2010
Cetuximab as Second-Line Therapy in Patients with Metastatic Esophageal Adenocarcinoma: A Phase II Southwest Oncology Group Study (S0415)
Introduction: Esophageal adenocarcinomas commonly express the epidermal growth factor receptor. This trial assessed the 6-month… 
Review
2008
Review
2008
Effect of Parecoxib on Postoperative Pain After Lumbar Spine Surgery: A Bicenter, Randomized, Double-Blinded, Placebo-Controlled Trial
Study Design. A bicenter randomized, patients, healthcare providers, and data collectors blind placebo-controlled trial in… 
Highly Cited
2006
Highly Cited
2006
Evidence for Interleukin‐10‐Mediated Inhibition of Cyclo‐ oxygenase‐2 Expression and Prostaglandin Production in Preterm Human Placenta
Problem  Interleukin‐10 (IL‐10) is thought to be a key cytokine for the maintenance of pregnancy. Here we examined the expression… 
Review
2006
Review
2006
Bile acids and Barrett's oesophagus: A sine qua non or coincidence?
Background. Barrett's oesophagus (BO), a premalignant condition associated with the development of oesophageal adenocarcinoma… 
Highly Cited
2004
Highly Cited
2004
Localized aggressive periodontitis is linked to human chromosome 1q25
Localized aggressive periodontitis (LAP; previously known as localized juvenile periodontitis) is one of the rapidly progressive… 
Highly Cited
2003
Highly Cited
2003
Progesterone Represses Interleukin-8 and Cyclo-Oxygenase-2 in Human Lower Segment Fibroblast Cells and Amnion Epithelial Cells1
Abstract Labor is preceded by cervical ripening through upregulation of interleukin (IL)-1β, IL-8, and increased prostaglandin… 
2003
2003
Bile Acid Induces Cyclo‐Oxygenase‐2 Expression in Cultured Human Pharyngeal Cells: A Possible Mechanism of Carcinogenesis in the Upper Aerodigestive Tract by Laryngopharyngeal Reflux
Objectives/Hypothesis Laryngopharyngeal reflux is a common event in patients with head and neck cancer. Bile acid is known to be… 
Highly Cited
2002
Highly Cited
2002
Salicylate Suppresses Macrophage Nitric-oxide Synthase-2 and Cyclo-oxygenase-2 Expression by Inhibiting CCAAT/Enhancer-binding Protein-β Binding via a Common Signaling Pathway*
We determined whether salicylate at pharmacological concentrations inhibits nitric-oxide synthase-2 (NOS-2) and cyclo-oxygenase-2… 
2001
2001
Distal bowel selectivity in the chemoprevention of experimental colon carcinogenesis by the non‐steroidal anti‐inflammatory drug nabumetone
Use of non‐steroidal anti‐inflammatory drugs (NSAIDs) for chemoprevention of colon cancer has been hindered by their potential… 
2001
2001
Heme oxygenase-1 induction by nitric oxide in RAW 264.7 macrophages is upregulated by a cyclo-oxygenase-2 inhibitor.
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