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cyclooxygenase 2

Known as: PTGS2, COX-2 Prostaglandin Synthase, PGHS-2 
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is… 
National Institutes of Health

Related topics

Related topics

15 relations
In BloodMT-CO2 genePTGS2 wt AlleleProcess of secretion

Narrower (3)

PTGS2 protein, humanPtgs2 protein, mousePtgs2 protein, rat

Broader (1)

Prostaglandin-Endoperoxide Synthase

Papers overview

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2014
2014
CALL FOR PAPERS Cardiovascular and Cerebrovascular Aging-New Mechanisms and Insights High-protein-low-carbohydrate diet: deleterious metabolic and cardiovascular effects depend on age
Tatiana Bedarida,* Stephanie Baron,* Emilie Vessieres, Francoise Vibert, Audrey Ayer, Carmen Marchiol-Fournigault, Daniel Henrion… 
2014
2014
MicroRNA-146 a and microRNA-146 b expression and anti-inflammatory function in human airway smooth muscle
Brian S. Comer, Blanca Camoretti-Mercado, Paul C. Kogut, Andrew J. Halayko, Julian Solway, and William T. Gerthoffer Department… 
2013
2013
In vitro antioxidant activity, lipoxygenase, cyclooxygenase-2 inhibition and DNA protection properties of Memecylon species.
Traditionally several species of Memecylon are used to cure skin problems. However, scientific validation of the plant as a… 
2007
2007
Design and synthesis of new rofecoxib analogs as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of the methanesulfonyl pharmacophore by a N-acetylsulfonamido bioisostere.
PURPOSE A group of 3,4-diaryl- 2(5H)furanones were synthesized to determine whether a N-acetylsulfonamido (SO2NHCOCH3) moiety… 
Review
2005
Review
2005
Cyclooxygenase inhibitor ketorolac or mast cell stabilizers: immunologic challenges in cancer therapy.
To the Editor: I have reviewed with interest the Featured Article by Mulshine et al. [(1)][1] reporting on the effects of a… 
2003
2003
Anti-inflammatory action of legume isoflavonoid sophoricoside through inhibition on cyclooxygenase-2 activity.
Soy is a main source of isoflavonoids which are of high dietary intake for the oriental population. In this study, the anti… 
2003
2003
팽대부 주위암에서 Cyclooxygenase-2 발현의 의의
Purpose: Cyclooxygenase-2 (COX-2) expression is upregulated in several types of human cancers and it has been suggested that COX… 
2001
2001
Therapeutic experience of hyperbaric oxygenation in entero-Behcet syndrome
TO THE EDITOR: This is the first report that confirms the efficacy of hyperbaric oxygen (HBO) therapy for an ileocecal ulcer in a… 
2001
2001
Cyclooxygenase-2: an attractive target for fruitful drug design
Cyclooxygenase, an enzyme involved in the conversion of C-20 acids to prostaglandins, exists in two isoforms. A third isoform has… 
Review
1999
Review
1999
Cyclooxygenase-2 as a target for prevention of colorectal cancer
COX-2 is an isoenzyme of cyclooxygenase that is increased in response to growth factors, cytokines, and other mitogenic stimuli…