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Prostaglandin-Endoperoxide Synthase

Known as: Endoperoxide Synthetase, Prostaglandin, Synthase, Prostaglandin H, Synthetase, Prostaglandin H2 
Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor… 
National Institutes of Health

Related topics

Related topics

19 relations
Enzyme GeneIn BloodOxidation-ReductionOxidoreductase Gene

Broader (2)

Multienzyme ComplexesOxygenases

Narrower (4)

PTGS1 protein, humancyclooxygenase 1cyclooxygenase 2cyclooxygenase-3

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair.
Preclinical and clinical studies suggest a possible role for cyclooxygenases in bone repair and create concerns about the use of… 
Highly Cited
2001
Highly Cited
2001
Prostaglandin E2 Increases Growth and Motility of Colorectal Carcinoma Cells*
Chronic use of nonsteroidal anti-inflammatory drugs results in a significant reduction of risk and mortality from colorectal… 
Highly Cited
1999
Highly Cited
1999
Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury.
Heme oxygenase (HO) catalyzes the conversion of heme to carbon monoxide, iron, and biliverdin, which is immediately reduced to… 
Review
1997
Review
1997
Properties and Regulation of Cytosolic Phospholipase A2 *
Membrane phospholipid is an important reservoir for the generation of bioactive mediators. Cellular phospholipases hydrolyze… 
Highly Cited
1985
Highly Cited
1985
Inflammatory mediators in late antigen-induced rhinitis.
To investigate the mechanisms responsible for the late-phase response in patients with allergies, we measured four biochemical… 
Highly Cited
1981
Highly Cited
1981
Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease.
Endogenous modulators of platelet aggregability and vascular tone may play a part in coronary-artery disease. We therefore… 
Highly Cited
1980
Highly Cited
1980
Leukotrienes are potent constrictors of human bronchi
Slow reacting substance of anaphylaxis (SRS-A) is released by various stimuli, including immunological challenge, and has long… 
Highly Cited
1980
Highly Cited
1980
PLATELET-MEMBRANE FATTY ACIDS, PLATELET AGGREGATION, AND THROMBOXANE FORMATION DURING A MACKEREL DIET
Highly Cited
1976
Highly Cited
1976
The chemical structure of prostaglandin X (prostacyclin).
Highly Cited
1973
Highly Cited
1973
Isolation and properties of intermediates in prostaglandin biosynthesis.
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