Prostaglandin-Endoperoxide Synthase

Known as: Endoperoxide Synthetase, Prostaglandin, Synthase, Prostaglandin H, Synthetase, Prostaglandin H2 
Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor… (More)

Topic mentions per year

Topic mentions per year

1968-2017
010020019682017

Papers overview

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Review
2016
Review
2016
High levels of cytokines, such as interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-6, are associated with chronic… (More)
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Highly Cited
2001
Highly Cited
2001
We show that high doses of salicylates reverse hyperglycemia, hyperinsulinemia, and dyslipidemia in obese rodents by sensitizing… (More)
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Highly Cited
1996
Highly Cited
1996
Colorectal cancer is the second leading cause of death from cancer in the United States. Continuous use of aspirin and other… (More)
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Highly Cited
1996
Highly Cited
1996
Peroxynitrite activates the cyclooxygenase activities of constitutive and inducible prostaglandin endoperoxide synthases by… (More)
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Highly Cited
1995
Highly Cited
1995
Prostaglandin endoperoxide synthase 2, also referred to as cyclooxygenase 2 (COX-2), is a key enzyme in the conversion of… (More)
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Highly Cited
1995
Highly Cited
1995
Cyclooxygenases 1 and 2 (COX-1 and COX-2) are key enzymes in prostaglandin biosynthesis and the target enzymes for the widely… (More)
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Highly Cited
1994
Highly Cited
1994
Aspirin (acetylsalicylate) treatment of human (h) prostaglandin endoperoxide H synthase (PGHS)-1 expressed in cos-1 cells caused… (More)
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Highly Cited
1993
Highly Cited
1993
Murine prostaglandin endoperoxide (PGH) synthase-1 and PGH synthase-2 expressed in cos-1 cells were found to be differentially… (More)
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Highly Cited
1993
Highly Cited
1993
Prostaglandin endoperoxide synthase (PHS) catalyzes the committed step in the biosynthesis of prostaglandins and thromboxane. We… (More)
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Highly Cited
1988
Highly Cited
1988
An oligonucleotide probe was used to isolate a clone encoding prostaglandin endoperoxide synthetase (cyclooxygenase, EC 1.14.99.1… (More)
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