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2-Oxoglutarate and ferrous iron-dependent oxygenases have emerged as an important family of human enzymes that catalyse… Expand Beyond established roles in collagen biosynthesis, hypoxic signaling and fatty acid metabolism, recent reports have now revealed… Expand The oxidative cleavage of carotenoids leads to the production of apocarotenoids and is catalyzed by a family of carotenoid… Expand Mononuclear non-heme ferrous iron dependent oxygenases and oxidases constitute an extended enzyme family that catalyze a wide… Expand Carotenoid cleavage products (apocarotenoids) are widespread in living organisms and exert key biological functions. In animals… Expand Oxygenases carry out the regio-, stereo- and chemoselective introduction of oxygen in a tremendous range of organic molecules… Expand Mononuclear nonheme-Fe(II)-dependent oxygenases comprise an extended family of oxidising enzymes, of which the 2-oxoglutarate… Expand Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the formation of prostaglandins by cyclo-oxygenases (COX). The discovery… Expand This is a critical review of the global distribution, sources of variation in toxicity, anatomical partitioning, metabolism, and… Expand Copper is an essential trace element in living systems, present in the parts per million concentration range. It is a key… Expand