PTGS1 protein, human

Known as: PTGS1, Prostaglandin H2 Synthase 1, Cyclooxygenase 
Prostaglandin G/H synthase 1 (599 aa, ~69 kDa) is encoded by the human PTGS1 gene. This protein plays a role in vasoconstriction, blood pressure… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2017
0102019762017

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2005
2005
Estradiol is biosynthesized from androgens by the aromatase enzyme complex. Previous studies suggest a strong association between… (More)
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2004
Highly Cited
2004
Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is found in grapes and various medical plants. Among cytotoxic, antifungal… (More)
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2004
2004
Two isoforms of prostaglandin H synthase (PTGS = COX) are key enzymes in prostaglandin synthesis and primary targets for aspirin… (More)
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2002
Highly Cited
2002
Nonsteroidal anti-inflammatory drugs are widely reported to inhibit carcinogenesis in humans and in rodents. These drugs are… (More)
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2002
Highly Cited
2002
This study was designed to investigate the expression and molecular signaling of cyclooxygenase-1 (COX-1) in cervical carcinomas… (More)
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Highly Cited
2000
Highly Cited
2000
Two isoforms of cyclooxygenase (COX) are known, and to date most studies have implicated COX-2, rather than COX-1, as the isoform… (More)
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Highly Cited
2000
Highly Cited
2000
Prostaglandins formed by cyclooxygenase-1 (COX-1) or COX-2 produce hyperalgesia in sensory nerve endings. To assess the relative… (More)
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1999
1999
Epidemiological and clinical studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit cyclooxygenase (COX… (More)
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1996
Highly Cited
1996
BACKGROUND & AIMS In the gastrointestinal tract, prostaglandins are implicated as important mediators of normal physiological… (More)
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1995
Highly Cited
1995
Aspirin exerts its anti-inflammatory effects through selective acetylation of serine 530 on prostaglandin H2 synthase (PGHS… (More)
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