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PTGS1 protein, human

Known as: PTGS1, Prostaglandin H2 Synthase 1, Cyclooxygenase 
Prostaglandin G/H synthase 1 (599 aa, ~69 kDa) is encoded by the human PTGS1 gene. This protein plays a role in vasoconstriction, blood pressure… 
National Institutes of Health

Related topics

Related topics

15 relations
Angiogenic ProcessArachidonic Acid Metabolism PathwayEGF-Like DomainEndoplasmic Reticulum

Broader (2)

Prostaglandin-Endoperoxide Synthasecyclooxygenase 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Potential Adverse Effects of Cyclooxygenase-2 Inhibition: Evidence from Animal Models of Inflammation
Cyclooxygenase (COX; prostaglandin H synthase, prostaglandin endoper-oxidase) is the key enzyme in the synthesis of the… 
2002
2002
Substrate Utilization Patterns During BTEX Biodegradation by an o-Xylene-Degrading Bacterium Ralstonia sp. PHS1
The biodegradation of BTEX components (benzene, toluene, ethylbenzene, o-xylene, m-xylene, and p-xylene) individually and in… 
2000
2000
Peroxidase activity in prostaglandin endoperoxide H synthase-1 occurs with a neutral histidine proximal heme ligand.
Prostaglandin endoperoxide H synthases-1 and -2 (PGHS-1 and -2) convert arachidonic acid to prostaglandin H(2) (PGH(2)), the… 
2000
2000
Advances in Brief Genetic Disruption of Ptgs-1 , as well as of Ptgs-2 , Reduces Intestinal Tumorigenesis in Min Mice
Two isoforms of cyclooxygenase (COX) are known, and to date most studies have implicated COX-2, rather than COX-1, as the isoform… 
1999
1999
An investigation into the biology and medicinal properties of Eucomis species.
Eucomis (Family Hyacinthaceae) are deciduous geophytes with long, narrow leaves and erect, densely packed flower spikes. The… 
1998
1998
SUPPRESSED THROMBOXANE PRODUCTION IN ENDOTOXIN‐DESENSITIZED THP‐1 CELLS IS NOT A RESULT OF DECREASED PROSTAGLANDIN H SYNTHASE ACTIVITY
ABSTRACT Pre-exposure of THP-1 cells to low concentrations of endotoxin (lipopolysaccharide, LPS) down-regulates thromboxane (Tx… 
1997
1997
Portal venous transfusion up-regulates Kupffer cell cyclooxygenase activity: a mechanism of immunosuppression in organ transplantation.
Portal venous transfusions (PVTs) of blood have been shown to induce significant immunosuppression in animal models of organ… 
1986
1986
9,11-Epoxy-9-homo-14-oxaprosta-5-enoic acid derivatives. Novel inhibitors of fatty acid cyclooxygenase.
A novel bicyclic prostaglandin analogue, [1R-[l alpha,2 beta (5Z),3 beta,4 alpha]]-7-[3-[(hexyloxy)methyl]- 7-oxabicyclo[2.2.1… 
1979
1979
Disorders in peripheral arterial system in asymptomatic elderly: plethysmographic semiology at rest, during postural, effort and pharmacological tests.
The vascular system of 30 old asymptomatic patients (average age 62.5 years) was studied by reflection plethysmography. The… 
1959
1959
Possible Relation between Carcinogenicity and Ease of Hydrolysis in vitro of Derivatives of 2-Aminofluorene
THE carcinogenicity of 2-acetylaminofluorene (I) administered orally to rats, was first reported in 1941 by Wilson, DeEds and…