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PTGS2 wt Allele

Known as: Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) wt Allele, COX2, hCOX-2 
Human PTGS2 wild type allele is located within 1q25.2-q25.3 and is approximately 9 kb in length. This allele, which encodes prostaglandin G/H… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Dietary fish oil containing ω3 highly unsaturated fatty acids has cardioprotective and anti-inflammatory effects. Prostaglandins… Expand
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Review
2001
Review
2001
Since the discovery in 1991 of a second isoform of prostaglandin endoperoxide H synthase (PGHS, or cyclooxygenase), there has… Expand
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Highly Cited
2001
Highly Cited
2001
Acetaminophen has similar analgesic and antipyretic properties to nonsteroidal antiinflammatory drugs (NSAIDs), which act via… Expand
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Highly Cited
1999
Highly Cited
1999
We investigated the mechanisms by which caffeic acid phenethyl ester (CAPE), a phenolic antioxidant, inhibited the stimulation of… Expand
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Highly Cited
1999
Highly Cited
1999
In this study we describe the generation of a transgenic mouse model with neuronal overexpression of the human cyclooxygenase-2… Expand
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Highly Cited
1997
Highly Cited
1997
Because of its structural similarity to polyunsaturated fatty acids, anandamide could serve as substrate for enzymes such as… Expand
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Highly Cited
1996
Highly Cited
1996
Evidence from epidemiological studies, clinical trials, and animal experiments indicates that inhibitors of prostaglandin… Expand
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Highly Cited
1995
Highly Cited
1995
The enzyme cyclo-oxygenase catalyses the oxygenation of arachidonic acid, leading to the formation of prostaglandins. Recently… Expand
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Highly Cited
1994
Highly Cited
1994
Human prostaglandin G/H synthase 1 and 2 were expressed in the baculovirus expression system and purified to high levels. Both… Expand
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Highly Cited
1994
Highly Cited
1994
Monocytes/macrophages are associated with chronic inflammatory lesions, such as periodontal disease and rheumatoid arthritis, in… Expand
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