PTGS2 gene

Known as: GRIPGHS, PTGS2, PHS II 
This gene is involved in mitogenesis, inflammation and angiogenesis.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND Regular use of aspirin after a diagnosis of colon cancer has been associated with a superior clinical outcome… (More)
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Review
2008
Review
2008
Both inflammation and angiogenesis are exacerbated by increased production of chemokines/cytokines, growth factors, proteolytic… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Candidate predictive biomarkers for irinotecan and oxaliplatin were assessed in 1,628 patients in Fluorouracil… (More)
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Highly Cited
2006
Highly Cited
2006
Curcumin, a major constituent of the spice turmeric, suppresses expression of the enzyme cyclooxygenase 2 (Cox-2) and has cancer… (More)
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Highly Cited
2003
Highly Cited
2003
Overuse injuries and trauma in tendon often involve acute or chronic pain and eventual matrix destruction. Anti-inflammatory… (More)
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Highly Cited
2002
Highly Cited
2002
Cyclooxygenase 2 (COX-2) mRNA, protein, and activity are transiently induced after infection of human fibroblasts with human… (More)
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Highly Cited
2001
Highly Cited
2001
Overproduction of inflammatory mediators by macrophages in response to Gram-negative LPS has been implicated in septic shock… (More)
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Highly Cited
2000
Highly Cited
2000
Aspirin therapy inhibits prostaglandin biosynthesis without directly acting on lipoxygenases, yet via acetylation of… (More)
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Highly Cited
2000
Highly Cited
2000
A tetracycline-regulated reporter system was used to investigate the regulation of cyclooxygenase 2 (Cox-2) mRNA stability by the… (More)
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Highly Cited
1993
Highly Cited
1993
Prostaglandin endoperoxide synthase (PHS) catalyzes the committed step in the biosynthesis of prostaglandins and thromboxane. We… (More)
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