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PTGS1 wt Allele

Known as: COX1, PGHS-1, COX3 
Human PTGS1 wild type allele is located within 9q32-q33.3 and is approximately 25 kb in length. This allele, which encodes prostaglandin G/H synthase… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
We identified a cis-prenyltransferase gene, neryl diphosphate synthase 1 (NDPS1), that is expressed in cultivated tomato (Solanum… Expand
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Highly Cited
2007
Highly Cited
2007
Dietary fish oil containing ω3 highly unsaturated fatty acids has cardioprotective and anti-inflammatory effects. Prostaglandins… Expand
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Review
2001
Review
2001
Since the discovery in 1991 of a second isoform of prostaglandin endoperoxide H synthase (PGHS, or cyclooxygenase), there has… Expand
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Highly Cited
1998
Highly Cited
1998
Prostaglandin endoperoxide H synthases-1 and -2 (PGHS-1 and -2) are the major targets of nonsteroidal anti-inflammatory drugs… Expand
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Highly Cited
1996
Highly Cited
1996
  • J. Otto, W. Smith
  • The Journal of Biological Chemistry
  • 1996
  • Corpus ID: 23967188
Previous studies of the crystal structure of the ovine prostaglandin endoperoxide H synthase-1 (PGHS-1)/S-flurbiprofen complex… Expand
Highly Cited
1995
Highly Cited
1995
Prostaglandin G/H synthase (PGHS), a key enzyme leading to the formation of prostaglandins, is the target of nonsteroidal… Expand
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Highly Cited
1995
Highly Cited
1995
The subcellular locations of prostaglandin endoperoxide synthase-1 and −2 (PGHS-1 and −2) were determined by quantitative… Expand
Highly Cited
1994
Highly Cited
1994
The aim of our study was to characterize a model of human prostaglandin endoperoxide synthase-2 (PGHS-2) expression allowing the… Expand
Highly Cited
1994
Highly Cited
1994
Aspirin (acetylsalicylate) treatment of human (h) prostaglandin endoperoxide H synthase (PGHS)-1 expressed in cos-1 cells caused… Expand
Highly Cited
1994
Highly Cited
1994
Human prostaglandin G/H synthase 1 and 2 were expressed in the baculovirus expression system and purified to high levels. Both… Expand