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PTGS1 wt Allele

Known as: COX1, PGHS-1, COX3 
Human PTGS1 wild type allele is located within 9q32-q33.3 and is approximately 25 kb in length. This allele, which encodes prostaglandin G/H synthase… 
National Institutes of Health

Related topics

Related topics

12 relations
9q32-q33.3Angiogenic ProcessHomeostasisHomo sapiens

Broader (1)

PTGS1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Prostaglandin-H-synthase (PGHS)-1 and -2 microtiter assays for the testing of herbal drugs and in vitro inhibition of PGHS-isoenzyms by polyunsaturated fatty acids from Platycodi radix.
2006
2006
Divergent cyclooxygenase responses to fatty acid structure and peroxide level in fish and mammalian prostaglandin H synthases
Prostanoid synthesis in mammalian tissues is regulated at the level of prostaglandin H synthase (PGHS) cyclooxygenase catalysis… 
2003
2003
Central Nervous System Prostaglandin Endoperoxide Synthase‐1 and −2 Responses to Oestradiol and Cerebral Hypoperfusion in Late‐Gestation Fetal Sheep
Previous work in this laboratory has demonstrated that cerebral hypoperfusion increases the expression of prostaglandin… 
2001
2001
The analysis of nonsteroidal antiinflammatory drug selectivity in prostaglandin G/H synthase (PGHS)-null cells
Abstract:Objectives: Nonsteroidal antiinflammatory drugs (NSAIDs) that are more selective for PGHS-2 maintain their… 
Highly Cited
2000
Highly Cited
2000
Aging increases PGHS-2-dependent vasoconstriction in rat mesenteric arteries.
During aging, the vascular endothelium changes functionally and morphologically. Although previous studies have shown that… 
1999
1999
Prostaglandin endoperoxide H synthase mRNA expression in the human amnion and decidua during pregnancy and in the amnion at preterm labour.
We have examined the expression of prostaglandin endoperoxide H synthase (PGHS) isoenzymes in the amnion and the decidua during… 
Highly Cited
1998
Highly Cited
1998
Localisation of prostaglandin endoperoxide H synthase (PGHS)‐1 and PGHS‐2 in bone following mechanical loading in vivo
Recent data suggests that induction of prostaglandin endoperoxide H synthase‐2 (PGHS‐2) is critical for the anabolic response of… 
1998
1998
Regulation of Prostaglandin G/H Synthase‐2 Expression by Interleukin‐1 in Human Osteoblast‐like Cells
Interleukin‐1 (IL‐1) is an important factor in bone metabolism, and its actions may be mediated in part via prostaglandins… 
Highly Cited
1994
Highly Cited
1994
Regulation of the two prostaglandin G/H synthases by parathyroid hormone, interleukin-1, cortisol, and prostaglandin E2 in cultured neonatal mouse calvariae.
A second prostaglandin G/H synthase (PGHS-2), encoded by a gene separate from that for the original PGHS (PGHS-1), has recently… 
Highly Cited
1990
Highly Cited
1990
Complex transcription from the extrachromosomal DNA encoding mitochondrial functions of Plasmodium yoelii
All tested members of genus Plasmodium contain tandemly arrayed, transcribed, extrachromosomal DNA with a unit length of 6.0 kb… 
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