• Publications
  • Influence
Triclosan is a potent inhibitor of estradiol and estrone sulfonation in sheep placenta.
The personal care product Triclosan, 5-chloro-2(2,4-dichlorophenoxy)-phenol, is widely used in consumer products as an antibacterial agent and is increasingly found in the environment as aExpand
  • 113
  • 5
Ontogeny and ultradian rhythms of adrenocorticotropin and cortisol in the late-gestation fetal horse.
Fetal maturation and the timing of parturition in both sheep and primates are thought to be controlled by the hypothalamic-pituitary-adrenal axis but little is known about the endocrinology of theExpand
  • 54
  • 3
  • PDF
Sinoaortic denervation attenuates the reflex responses to hypotension in fetal sheep.
  • C. Wood
  • Medicine
  • The American journal of physiology
  • 1 May 1989
Hypotension in fetal sheep stimulates reflex decreases in heart rate and increases in the secretion of several hormones, including adrenocorticotropin (ACTH), cortisol, vasopressin, and renin.Expand
  • 39
  • 3
Control of parturition in ruminants.
  • C. Wood
  • Biology, Medicine
  • Journal of reproduction and fertility. Supplement
  • 5 April 2019
Parturition is a process which, when set into motion, occurs to completion. This review concerns the control of parturition in ruminants. Parturition is an endocrine event, dependent upon theExpand
  • 57
  • 3
  • PDF
Expression of ENaC subunits, chloride channels, and aquaporins in ovine fetal lung: ontogeny of expression and effects of altered fetal cortisol concentrations.
Transition of the epithelium of the fetal lung from fluid secretion to fluid reabsorption requires changes in the expression of ion channels. Corticosteroids regulate expression of several of theseExpand
  • 15
  • 3
  • PDF
Cortisol stimulates proliferation and apoptosis in the late gestation fetal heart: differential effects of mineralocorticoid and glucocorticoid receptors.
We have previously found that modest chronic increases in maternal cortisol result in an enlarged fetal heart. To explore the mechanisms of this effect, we used intrapericardial infusions of aExpand
  • 33
  • 2
  • PDF
Cardiac corticosteroid receptors mediate the enlargement of the ovine fetal heart induced by chronic increases in maternal cortisol.
Previous studies have demonstrated that modest, physiologically relevant increases in maternal cortisol in late gestation result in enlargement of the fetal heart. In this study, we investigated theExpand
  • 33
  • 2
  • PDF
Estrogen and androgen influence hypothalamic AVP and CRF concentrations in fetal and adult sheep
The present study tested the hypothesis that action of sex steroids on the hypothalamus-pituitary-adrenal (HPA) axis is measurable in the hypothalamus. Late-gestation fetal sheep were treated (5Expand
  • 19
  • 2
Effects of prior oral contraceptive use and soy isoflavonoids on estrogen-metabolizing cytochrome P450 enzymes
Estrogen exposure and metabolism may play an important role in the development of estrogen-sensitive cancers in postmenopausal women. In this study we investigated whether past oral contraceptiveExpand
  • 19
  • 2
Influence of Estradiol and Androstenedione on ACTH and Cortisol Secretion in the Ovine Fetus
  • C. Wood, C. Saoud
  • Medicine
  • The Journal of the Society for Gynecologic…
  • 1 November 1997
Objective: To test the hypothesis that physiologic increases in fetal plasma 17β-estradiol and androstenedione modulate the activity of the fetal hypothalamic-pituitary-adrenal (HPA) axis. Methods:Expand
  • 16
  • 2