Endoplasmic Reticulum

Known as: Ergastoplasm, Reticulum, Endoplasmic, ER 
A system of cisternae in the CYTOPLASM of many cells. In places the endoplasmic reticulum is continuous with the plasma membrane (CELL MEMBRANE) or… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1952-2017
01000200019522016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The secretory capacity of a cell is constantly challenged by physiological demands and pathological perturbations. To adjust and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2017
Review
2017
The maintenance of a fluid lipid bilayer is key for membrane integrity and cell viability. We are only beginning to understand… (More)
Is this relevant?
Review
2017
Review
2017
The 78-kDa glucose-regulated protein GRP78, also known as BiP and HSP5a, is a multifunctional protein with activities far beyond… (More)
  • figure 1
Is this relevant?
Review
2017
Review
2017
Cancer cells are exposed to various intrinsic and extrinsic factors that disrupt protein homeostasis, producing endoplasmic… (More)
Is this relevant?
Review
2016
Review
2016
Tumor cells are often exposed to intrinsic and external factors that alter protein homeostasis, thus producing endoplasmic… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Juxtaposition between endoplasmic reticulum (ER) and mitochondria is a common structural feature, providing the physical basis… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Unfolded and malfolded client proteins impose a stress on the endoplasmic reticulum (ER), which contributes to cell death in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
  • Marcella Calfon, Huiqing Zeng, +5 authors David Ron
  • Nature
  • 2002
The unfolded protein response (UPR), caused by stress, matches the folding capacity of endoplasmic reticulum (ER) to the load of… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Protein synthesis and the folding of the newly synthesized proteins into the correct three-dimensional structure are coupled in… (More)
  • figure 1
  • figure 3
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Cellular stress, particularly in response to toxic and metabolic insults that perturb function of the endoplasmic reticulum (ER… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?