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  • K. Lee, W. Tirasophon, +6 authors R. Kaufman
  • Medicine, Biology
  • Genes & development
  • 2002 (First Publication: 15 February 2002)
  • All eukaryotic cells respond to the accumulation of unfolded proteins in the endoplasmic reticulum (ER) by signaling an adaptive pathway termed the unfolded protein response (UPR). In yeast, a type-IExpand
  • K. Yamamoto, H. Yoshida, K. Kokame, R. Kaufman, K. Mori
  • Biology, Medicine
  • Journal of biochemistry
  • 2004 (First Publication: 1 September 2004)
  • ATF6 and XBP1 are transcription factors activated specifically in response to endoplasmic reticulum (ER) stress. Three cis-acting elements capable of binding to ATF6, XBP1 or both have beenExpand