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Aromatase

Known as: aromatases, CYP19, CYP19 Protein 
An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19… 
National Institutes of Health

Related topics

Related topics

34 relations

Narrower (5)

AROMATASE EXCESS SYNDROMEAromatase deficiencyCYP19a protein, zebrafishCYP19b protein, zebrafish

Broader (1)

Aryl Hydrocarbon Hydroxylases
Biologic DevelopmentCYP19A1 geneCYP19A1 protein, humanCYP19A1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Endocrine disruption in thicklip grey mullet (Chelon labrosus) from the Urdaibai Biosphere Reserve (Bay of Biscay, Southwestern Europe).
2008
2008
Steroidogenic gene expression during sex determination in the frog Rana rugosa.
Highly Cited
2008
Highly Cited
2008
EP2 and EP4 Receptors Regulate Aromatase Expression in Human Adipocytes and Breast Cancer Cells
Cytochrome P450 aromatase (aromatase), a product of the CYP19 gene, catalyzes the synthesis of estrogens from androgens. Because… 
2005
2005
Promoter-2-derived Cyp19 expression in bovine granulosa cells coincides with gene-specific DNA hypo-methylation
Highly Cited
2002
Highly Cited
2002
Cloning and characterization of a novel endothelial promoter of the human CYP19 (aromatase P450) gene that is up-regulated in breast cancer tissue.
Intratumoral expression of aromatase P450 (P450arom) promotes the growth of breast tumors via increased local estrogen… 
1999
1999
Imidazole substituted biphenyls: a new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer.
Highly Cited
1997
Highly Cited
1997
Distribution of aromatase cytochrome P450 messenger ribonucleic acid in adult rhesus monkey brains.
The conversion of androgens to estrogens by aromatase cytochrome P450 (P450arom) is an important step in the mechanism of… 
Highly Cited
1982
Highly Cited
1982
Inhibition and inactivation of estrogen synthetase (aromatase) by fluorinated substrate analogues.
19,19-Difluoroandrost-4-ene-3,17-dione (1) and 19-fluorcandrost-4-ene-3,17-dione (2) have been synthesized, and the interaction… 
1982
1982
Multiple forms of aromatase and response of breast cancer aromatase to antiplacental aromatase II antibodies.
Two distinct aromatase-active protein complexes are solubilized by use of deoxycholate and separated by diethylamino-ethyl… 
1976
1976
The protease problem in Neurospora. Structural modification of the arom multienzyme system during its extraction and isolation.
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