Aromatase

Known as: aromatases, CYP19, CYP19 Protein 
An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19… (More)

Topic mentions per year

Topic mentions per year

1974-2018
010020019742018

Papers overview

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Review
2016
Review
2016
Mutations of the retinoblastoma tumor-suppressor gene (RB1) or components regulating the CDK-RB-E2F pathway have been identified… (More)
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Highly Cited
2011
Highly Cited
2011
Elevated circulating estrogen levels are associated with increased risk of breast cancer in obese postmenopausal women. Following… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Ovarian suppression plus tamoxifen is a standard adjuvant treatment in premenopausal women with endocrine-responsive… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Adjuvant aromatase inhibitor therapy is well established in postmenopausal women with hormone receptor-positive breast… (More)
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Highly Cited
2002
Highly Cited
2002
Various pesticides known or suspected to interfere with steroid hormone function were screened in H295R cells for effects on… (More)
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Highly Cited
2001
Highly Cited
2001
The expression of aromatase, the enzyme that catalyzes the biosynthesis of estrogens from precursor androgens, is increased in… (More)
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Highly Cited
2000
Highly Cited
2000
There is increasing concern that certain chemicals in the environment can cause endocrine disruption in exposed humans and… (More)
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Highly Cited
1999
Highly Cited
1999
It is well established that spermatogenesis is controlled by gonadotrophins and testosterone. However, a role for estrogens in… (More)
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Highly Cited
1999
Highly Cited
1999
Based on experimental and epidemiological evidence it is hypothesized that estrogen increases breast cancer risk by increasing… (More)
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Highly Cited
1995
Highly Cited
1995
The aromatase enzyme complex catalyzes the conversion of androgens to estrogens in a wide variety of tissues, including the ovary… (More)
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