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CYP19A1 gene

Known as: P-450AROM, CYP19, CYTOCHROME P450, SUBFAMILY XIX 
This gene is involved in development and estrogen metabolism.
National Institutes of Health

Related topics

Related topics

13 relations
AromataseBiologic DevelopmentCYP19A1 protein, humanEndometriosis

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CYP19A1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism.
Cytochrome P450 aromatase (aromatase), a product of the CYP19 gene, catalyzes the synthesis of estrogens from androgens. Given… 
Review
2003
Review
2003
Aromatase activity in the European sea bass (Dicentrarchus labrax L.) brain. Distribution and changes in relation to age, sex, and the annual reproductive cycle.
Highly Cited
2003
Highly Cited
2003
Prostaglandin E2 regulates aromatase activity and expression in human adipose stromal cells via two distinct receptor subtypes.
The aromatase enzyme complex, located primarily in the stromal cells of breast tumors, catalyzes estrogen biosynthesis and is… 
Highly Cited
2002
Highly Cited
2002
Aromatase Inhibitors Block Natural Sex Change and Induce Male Function in the Protandrous Black Porgy, Acanthopagrus schlegeli Bleeker: Possible Mechanism of Natural Sex Change1
Abstract The objectives of the present study were to investigate the effects of oral administration of aromatase inhibitors on… 
Highly Cited
2001
Highly Cited
2001
Rapid and reversible inhibition of brain aromatase activity.
Many actions of androgens require their conversion via the enzyme aromatase into oestrogens. Changes in brain aromatase activity… 
Highly Cited
1998
Highly Cited
1998
A rare CYP19 (aromatase) variant may increase the risk of breast cancer.
The aromatase P450 (coded by the CYP19 gene) is responsible for the rate limiting step in the metabolism of C19 steroids to… 
Highly Cited
1995
Highly Cited
1995
Aromatase in human endometrial carcinoma and hyperplasia. Immunohistochemical, in situ hybridization, and biochemical studies.
The expression of P450 aromatase and other steroidogenic enzymes were evaluated in 42 endometrioid endometrial carcinomas, 23… 
Highly Cited
1989
Highly Cited
1989
Localization of aromatase in synaptosomal and microsomal subfractions of quail (Coturnix coturnix japonica) brain.
The subcellular distribution patterns of aromatase, 5 alpha- and 5 beta-reductase in the hypothalamus/preoptic area of Japanese… 
Highly Cited
1988
Highly Cited
1988
Novel properties of human placental aromatase as cytochrome P-450: purification and characterization of a unique form of aromatase.
Aromatase has been purified to homogeneity from human placental microsomes based on detection of its catalytic activities in the… 
Highly Cited
1986
Highly Cited
1986
Formation of behaviorally effective 17 beta-estradiol in the dove brain: steroid control of preoptic aromatase.
The preoptic area (POA) of the male dove is a known target area for separable behavioral actions of testosterone and 17 beta… 
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