TbRab2p, a marker for the endoplasmic reticulum of Trypanosoma brucei, localises to the ERGIC in mammalian cells.

@article{Field1999TbRab2pAM,
  title={TbRab2p, a marker for the endoplasmic reticulum of Trypanosoma brucei, localises to the ERGIC in mammalian cells.},
  author={Holly Field and Bassam R Ali and Trevor Sherwin and Keith Gull and Simon Croft and Mark C. Field},
  journal={Journal of cell science},
  year={1999},
  volume={112 ( Pt 2)},
  pages={147-56}
}
The Rab family of small GTPases is a subset of the Ras superfamily. Rabs regulate the flux through individual steps of the intracellular membrane trafficking pathway, such as ER-to-Golgi transport, probably by controlling SNARE complex assembly. In Trypanosoma brucei a number of Rab proteins have been isolated by EST analysis; here we characterise one of these, TbRab2p (originally designated Trab1p), which is a member of the Ypt1p subfamily of Rab proteins. Recombinant TbRab2p is capable of… CONTINUE READING