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EGF-Like Domain

A sequence of about thirty to forty amino-acid residues long found in the sequence of epidermal growth factor (EGF) has been shown to be present, in… 
National Institutes of Health

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50 relations
ADAM12 protein, humanATRN protein, humanBTC protein, humanCELSR1 cadherin, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Synthetic Human NOTCH1 EGF Modules Unraveled Molecular Mechanisms for the Structural and Functional Roles of Calcium Ions and O-Glycans in the Ligand-Binding Region.
The Notch signaling pathway is an evolutionarily highly conserved mechanism that operates across multicellular organisms and is… 
2016
2016
Structural Characterization and Alternate Splicing of the Gene Encoding the Preadipocyte EGF-like Protein Pref-11 -
Preadipocyte factor 1 (pref-1), a member of the EGF-like protein family, is a transmembrane protein with six tandem EGF-like… 
2012
2012
A Potent Anti-HB-EGF Monoclonal Antibody Inhibits Cancer Cell Proliferation and Multiple Angiogenic Activities of HB-EGF
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the epidermal growth factor family and has a… 
2005
2005
NGX6 gene inhibits cell proliferation and plays a negative role in EGFR pathway in nasopharyngeal carcinoma cells
Nasopharyngeal carcinoma (NPC) is a common cancer in South China but is rare in other parts of the world. A novel NPC‐related… 
2004
2004
Identification and validation of anti-TMEFF2-Auristatin E conjugated antibodies in the treatment of prostate cancer.
2557 Background: Current treatments for advanced stage prostate cancer are largely ineffectual, resulting in high mortality and… 
2002
2002
Receptor-Based Antidote for Diphtheria
ABSTRACT Although equine diphtheria antitoxin may be an effective therapy for human diphtheria, its use often induces serum… 
2000
2000
The human homologue of flamingo, EGFL2, encodes a brain-expressed large cadherin-like protein with epidermal growth factor-like domains, and maps to chromosome 1p13.3-p21.1.
The epidermal growth factor (EGF)-like domain, spanning approximately 50 amino acids and with three disulphide bonds, is the… 
Highly Cited
1999
Highly Cited
1999
Interaction of metargidin (ADAM-15) with αvβ3 and α5β1 integrins on different haemopoietic cells
Metargidin (ADAM-15) is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain… 
1989
1989
Prostaglandin endoperoxide synthase contains an EGF‐like domain
1987
1987
MAPPING OF 6 MONOCLONAL ANTIBODIES TO HUMAN FACTOR IX
In order to map the regions of human factor IX recognized by monoclonal antibodies we have inserted random fragments of the… 
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