Skip to search formSkip to main contentSkip to account menu

BTC protein, human

Known as: betacellulin protein, human, Beta-Cellulin, Beta Cellulin 
Betacellulin (80 aa, ~9 kDa) is encoded by the human BTC gene. This protein is involved in epidermal growth factor receptor family signaling pathways… 
National Institutes of Health

Related topics

Related topics

14 relations
Angiogenic ProcessBTC geneCell Proliferation Regulatory ProcessEGF-Like Domain

Broader (1)

betacellulin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Amphiregulin Exosomes Increase Cancer Cell Invasion
Highly Cited
2010
Highly Cited
2010
Breast cancer knowledge among women with learning disabilities and their experiences of breast mammography
As the life expectancy of people with learning disabilities rises, so too do cancer prevalence rates in people with learning… 
Highly Cited
2003
Highly Cited
2003
Defective valvulogenesis in HB‐EGF and TACE‐null mice is associated with aberrant BMP signaling
Heparin‐binding epidermal growth factor (HB‐EGF) and betacellulin (BTC) are activating ligands for EGF receptor (EGFR/ErbB1) and… 
Highly Cited
2003
Highly Cited
2003
Nanopore Structure and Sorption Properties of Cu-BTC Metal-Organic Framework
Grand canonical Monte Carlo simulations in conjunction with high-resolution low-pressure argon adsorption experiments were… 
Highly Cited
2002
Highly Cited
2002
The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides.
The ErbB1 and ErbB2 receptor tyrosine kinases (RTKs) play important roles in the development of numerous types of human cancer… 
Highly Cited
2000
Highly Cited
2000
Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells.
Head and neck squamous cell carcinomas (HNSCCs) are characterized by a marked propensity for local invasion and dissemination to… 
Highly Cited
2000
Highly Cited
2000
Epidermal growth factor receptor vIII enhances tumorigenicity in human breast cancer.
Epidermal growth factor receptor vIII (EGFRvIII) is a tumor-specific, ligand-independent, constitutively active variant of the… 
Highly Cited
2000
Highly Cited
2000
Ionic selectivity of low-affinity ratiometric calcium indicators: mag-Fura-2, Fura-2FF and BTC.
Accurate measurement of elevated intracellular calcium levels requires indicators with low calcium affinity and high selectivity… 
Highly Cited
1998
Highly Cited
1998
Growth Factor-Mediated Proliferation and Differentiation of Insulin-Producing INS-1 and RINm5F Cells: Identification of Betacellulin as a Novel β-Cell Mitogen.
It is not clear which growth factors are crucial for the survival, proliferation, and differentiation of pancreatic β-cells. We… 
Highly Cited
1996
Highly Cited
1996
Human betacellulin, a member of the EGF family dominantly expressed in pancreas and small intestine, is fully active in a monomeric form.
Betacellulin (BTC) was found to be expressed mainly in human pancreas and small intestine. This finding suggests that BTC… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)