BTC protein, human

Known as: betacellulin protein, human, Beta-Cellulin, Beta Cellulin 
Betacellulin (80 aa, ~9 kDa) is encoded by the human BTC gene. This protein is involved in epidermal growth factor receptor family signaling pathways… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
PURPOSE To explore the prognostic and/or predictive value of human epidermal growth factor receptor 2 (HER2) pathway-related… (More)
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Highly Cited
2011
Highly Cited
2011
Autocrine, paracrine, and juxtacrine are recognized modes of action for mammalian EGFR ligands including EGF, TGF-α (TGF… (More)
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2008
2008
OBJECTIVE Identify molecular targets for development of tumor-specific pharmacotherapeutics aimed at treating vestibular… (More)
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Review
2008
Review
2008
There is a great unmet medical need in the area of cancer treatment. A potential therapeutic target for intervention in cancer is… (More)
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Highly Cited
2004
Highly Cited
2004
Before ovulation in mammals, a cascade of events resembling an inflammatory and/or tissue remodeling process is triggered by… (More)
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Highly Cited
2003
Highly Cited
2003
Heparin-binding epidermal growth factor (HB-EGF) and betacellulin (BTC) are activating ligands for EGF receptor (EGFR/ErbB1) and… (More)
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Highly Cited
2002
Highly Cited
2002
The ErbB1 and ErbB2 receptor tyrosine kinases (RTKs) play important roles in the development of numerous types of human cancer… (More)
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Highly Cited
2000
Highly Cited
2000
Epidermal growth factor receptor vIII (EGFRvIII) is a tumor-specific, ligand-independent, constitutively active variant of the… (More)
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2000
2000
Neu differentiation factor (NDF; also known as neuregulin) induces a pleiotropic cellular response that is cell type-dependent… (More)
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Highly Cited
1997
Highly Cited
1997
Neu differentiation factor (NDF), a member of the epidermal growth factor (EGF)-related peptide family, activates ErbB2 via… (More)
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