Prostaglandin E2

Known as: PGE2, 5-Heptenoic Acid, 7-(3-Hydroxy-2-(3-Hydroxy-1-Octenyl)-5-Oxocyclopentyl)- (8CI), Prosta-5,13-Dien-1-Oic Acid, 11,15-Dihydroxy-9-Oxo-, (5Z,11alpha,13E,15S)- 
A prostaglandin with 2 double bonds that is generated by the action of prostaglandin E synthases on prostaglandin H2. Prostaglandin E2 is a mediator… (More)
National Institutes of Health

Papers overview

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Review
2012
Review
2012
PGE(2), an essential homeostatic factor, is also a key mediator of immunopathology in chronic infections and cancer. The impact… (More)
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Highly Cited
2007
Highly Cited
2007
Haematopoietic stem cell (HSC) homeostasis is tightly controlled by growth factors, signalling molecules and transcription… (More)
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Highly Cited
2005
Highly Cited
2005
Mesenchymal stem cells (MSCs) are multipotent cells found in several adult tissues. Transplanted allogeneic MSCs can be detected… (More)
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Highly Cited
2003
Highly Cited
2003
Over the past decade cyclooxygenase-2-derived prostaglandins have been implicated in the development and progression of many… (More)
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Highly Cited
2001
Highly Cited
2001
Chronic use of nonsteroidal anti-inflammatory drugs results in a significant reduction of risk and mortality from colorectal… (More)
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Highly Cited
2000
Highly Cited
2000
Here we report the molecular identification of membrane-bound glutathione (GSH)-dependent prostaglandin (PG) E(2) synthase (mPGES… (More)
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Highly Cited
2000
Highly Cited
2000
Here we report the molecular identification of cytosolic glutathione (GSH)-dependent prostaglandin (PG) E(2) synthase (cPGES), a… (More)
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Highly Cited
1998
Highly Cited
1998
Previously, we have shown that forced expression of prostaglandin endoperoxide synthase-2 [also called cyclooxygenase (COX) 2… (More)
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Highly Cited
1998
Highly Cited
1998
Astrocytes in the brain form an intimately associated network with neurons. They respond to neuronal activity and synaptically… (More)
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Highly Cited
1997
Highly Cited
1997
Because of its structural similarity to polyunsaturated fatty acids, anandamide could serve as substrate for enzymes such as… (More)
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