Skip to search formSkip to main contentSkip to account menu

Pregnanolone

Known as: 3-Hydroxypregnan-20-one, Pregnan-20-one, 3-hydroxy-, (3alpha,5beta)-, 3 alpha-Hydroxy-5 beta-pregnan-20-one 
A pregnane found in the urine of pregnant women and sows. It has anesthetic, hypnotic, and sedative properties.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
  • D. Reddy
  • Progress in Brain Research
  • 2010
  • Corpus ID: 35380415
Highly Cited
2006
Highly Cited
2006
Inhibitory neurotransmission mediated by GABAA receptors can be modulated by the endogenous neurosteroids, allopregnanolone and… 
Highly Cited
2000
Highly Cited
2000
Neuroactive steroids are synthesized de novo in brain, yet their physiological significance remains elusive. We provide… 
Highly Cited
1999
Highly Cited
1999
The neurosteroid 3alpha-hydroxysteroid-5alpha-pregnan-20-one (allopregnanolone) acts as a positive allosteric modulator of gamma… 
Highly Cited
1998
Highly Cited
1998
The relation between changes in brain and plasma concentrations of neurosteroids and the function and structure of gamma… 
Highly Cited
1997
Highly Cited
1996
Highly Cited
1996
Fluoxetine administered intraperitoneally to sham-operated or adrenalectomized/castrated (ADX/CX) male rats dose-dependently (2.9… 
Highly Cited
1995
Highly Cited
1995
Previous studies from this laboratory have shown that progesterone (PROG) treatment in ovariectomized rats produces an anti… 
Highly Cited
1991
Highly Cited
1991
A 3 alpha-hydroxy A-ring-reduced metabolite of progesterone, 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone), and one…