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Pregnanes

Known as: pregnane compound, Pregnane, Pregnanes [Chemical/Ingredient] 
Saturated derivatives of the steroid pregnane. The 5-beta series includes PROGESTERONE and related hormones; the 5-alpha series includes forms… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Background— Oral estrogen therapy increases the risk of venous thromboembolism (VTE) in postmenopausal women. Transdermal… Expand
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Highly Cited
2005
Highly Cited
2005
Bile acids, steroids, and drugs activate steroid and xenobiotic receptor pregnane X receptor (PXR; NR1I2), which induces human… Expand
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Review
2004
Review
2004
The vectorial transport of bile salts from blood into bile is essential for the generation of bile flow, solubilization of… Expand
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Review
2003
Review
2003
The metabolic nuclear receptors act as metabolic and toxicological sensors, enabling the organism to quickly adapt to… Expand
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Highly Cited
2001
Highly Cited
2001
Although CYP3A induction by dexamethasone has been extensively documented, its mechanism is still unclear because both the role… Expand
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Highly Cited
2001
Highly Cited
2001
Sister of P-glycoprotein (SPGP) is the major hepatic bile salt export pump (BSEP). BSEP/SPGP expression varies dramatically among… Expand
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Review
1999
Review
1999
I. Introduction II. Nuclear Receptors: General Concepts A. Anatomy of nuclear receptors B. Mechanisms of action III. Orphan… Expand
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Highly Cited
1998
Highly Cited
1998
Steroid hormones exert profound effects on differentiation, development, and homeostasis in higher eukaryotes through… Expand
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Highly Cited
1998
Highly Cited
1998
Nuclear receptors regulate metabolic pathways in response to changes in the environment by appropriate alterations in gene… Expand
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Highly Cited
1993
Highly Cited
1993
Several 3 alpha-hydroxysteroids accumulate in the brain after local synthesis or after metabolization of steroids that are… Expand
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