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Antidepressant activity of curcumin: involvement of serotonin and dopamine system
TLDR
The coadministration of curcumin along with piperine may prove to be a useful and potent natural antidepressant approach in the management of depression. Expand
Minocycline attenuates the development of diabetic neuropathic pain: possible anti-inflammatory and anti-oxidant mechanisms.
TLDR
The results of the present study strongly suggest that activated microglia are involved in the development of experimental diabetic neuropathy and minocycline exerted its effect probably by inhibition of neuroimmune activation ofmicroglia. Expand
Withania somnifera: An Indian ginseng
TLDR
The present review discusses the pharmacological basis of the use of W. somnifera in various central nervous system (CNS) disorders, particularly its indication in epilepsy, stress and neurodegenerative diseases such as Parkinson's and Alzheimer's disorders, tardive dyskinesia, cerebral ischemia, and even in the management of drug addiction. Expand
Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders
TLDR
The pharmacological basis of the use of berberine in various central nervous system and related disorders is discussed and its protective effect in Alzheimer's, cerebral ischemia, mental depression, schizophrenia and anxiety are highlighted. Expand
CURCUMIN, THE ACTIVE PRINCIPLE OF TURMERIC (CURCUMA LONGA), AMELIORATES DIABETIC NEPHROPATHY IN RATS
TLDR
Results provide confirmatory evidence of oxidative stress in diabetic nephropathy and point towards the possible anti‐oxidative mechanism being responsible for the nephroprotective action of curcumin. Expand
Resveratrol, a Polyphenolic Phytoalexin, Attenuates Diabetic Nephropathy in Rats
TLDR
The present study reinforces the important role of oxidative stress in diabetic kidney and points towards the possible antioxidative mechanism being responsible for the renoprotective action of resveratrol. Expand
Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: participation of nitric oxide and TNF‐alpha
TLDR
Results indicate an antinociceptive activity of resveratrol and curcumin and point towards the beneficial effect of these combinations with insulin in attenuating diabetic neuropathic pain, possibly through the participation of NO and TNF‐α. Expand
Anti-depressant like effect of curcumin and its combination with piperine in unpredictable chronic stress-induced behavioral, biochemical and neurochemical changes
TLDR
This study provided a scientific rationale for the use of curcumin and its co-administration with piperine in the treatment of depressive disorders. Expand
Studies on modulation of feeding behavior by atypical antipsychotics in female mice
TLDR
The study further confirms the involvement of dopamine D1, D2 and serotonergic receptor involvement in clozapine-mediated hyperphagia and confirms that theSerotonergic agents may prove useful to counteract antipsychotic-induced obesity. Expand
Nitric oxide and major depression.
TLDR
Nitric oxide based antidepressants can be the future drugs of choice for major depression, particularly in the treatment of pharmacoresistant depression. Expand
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