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Peptide Initiation Factors

Known as: Initiation Factors, Peptide, Translational Initiation Factor, Translation Initiation Factor 
One of several soluble proteins involved in the initiation of protein or RNA synthesis.(On-line Medical Dictionary)
National Institutes of Health

Related topics

Related topics

28 relations
Eukaryotic Initiation Factor-2BEukaryotic Initiation Factor-4FEukaryotic Translation Initiation Factor 5, humanGenetic Translation Process
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Narrower (12)

IDI2 protein, Hordeum vulgareIF2 protein, archaealLepA protein, E coliaIF-5A
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Broader (1)

Peptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
The Organizing Principles of Eukaryotic Ribosome Recruitment.
The stage at which ribosomes are recruited to messenger RNAs (mRNAs) is an elaborate and highly regulated phase of protein… Expand
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Review
2018
Review
2018
Functions and Signaling Pathways of Amino Acids in Intestinal Inflammation
Intestine is always exposed to external environment and intestinal microorganism; thus it is more sensitive to dysfunction and… Expand
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Review
2010
Review
2010
The mechanism of eukaryotic translation initiation and principles of its regulation
Protein synthesis is principally regulated at the initiation stage (rather than during elongation or termination), allowing rapid… Expand
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Highly Cited
2003
Highly Cited
2003
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress.
Eukaryotic cells respond to unfolded proteins in their endoplasmic reticulum (ER stress), amino acid starvation, or oxidants by… Expand
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Highly Cited
2002
Highly Cited
2002
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
Tuberous sclerosis (TSC) is an autosomal dominant disorder characterized by the formation of hamartomas in a wide range of human… Expand
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Highly Cited
2002
Highly Cited
2002
Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action
mTOR controls cell growth, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding… Expand
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Highly Cited
2000
Highly Cited
2000
Regulated translation initiation controls stress-induced gene expression in mammalian cells.
Protein kinases that phosphorylate the alpha subunit of eukaryotic initiation factor 2 (eIF2alpha) are activated in stressed… Expand
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Highly Cited
2000
Highly Cited
2000
Perk is essential for translational regulation and cell survival during the unfolded protein response.
Malfolded proteins in the endoplasmic reticulum (ER) inhibit translation initiation. This response is believed to be mediated by… Expand
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Review
1999
Review
1999
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation.
Eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that mediates recruitment of ribosomes to mRNA. This… Expand
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Review
1991
Review
1991
Structural features in eukaryotic mRNAs that modulate the initiation of translation.
  • M. Kozak
  • The Journal of biological chemistry
  • 1991
    • Corpus ID: 13805548
In higher eukaryotes, translation is modulated at the level of initiation by five aspects of mRNA structure: (i) the m7G cap; (ii… Expand
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