Skip to search formSkip to main contentSkip to account menu

Eukaryotic Initiation Factor-4F

Known as: Eukaryotic Translation Initiation Factor 4F, Protein Initiation Factor EIF-4F, EIF4F Translation Initiation Complex 
A protein complex comprised of a heterotetrameric core, eukaryotic initiation factor 4A, 4E, and 4 gamma, bound to other factors; the exact… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (1)

EIF-(iso)4F
EIF4A2 wt AlleleEIF4E wt AlleleEIF4G1 wt AlleleEukaryotic Initiation Factor 4A-I, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Phosphorylation of eIF4E by Mnk-1 enhances HSV-1 translation and replication in quiescent cells.
Although the activity of the translation initiation factor eIF4F is regulated in part by translational repressors (4E-BPs) that… 
Highly Cited
2004
Highly Cited
2004
What determines whether mammalian ribosomes resume scanning after translation of a short upstream open reading frame?
If the 5'-proximal AUG triplet in a mammalian mRNA is followed by a short open reading frame (sORF), a significant fraction of… 
Highly Cited
2001
Highly Cited
2001
Suppression of cap-dependent translation in mitosis.
Cap-dependent translation is mediated by eIF4F, a protein complex composed of three subunits as follows: eIF4E, which recognizes… 
Highly Cited
2001
Highly Cited
2001
Cell cycle-dependent phosphorylation of the translational repressor eIF-4E binding protein-1 (4E-BP1)
Highly Cited
1999
Highly Cited
1999
Identification of eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray.
Although most eukaryotic mRNAs need a functional cap binding complex eIF4F for efficient 5' end- dependent scanning to initiate… 
Highly Cited
1998
Highly Cited
1998
Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation
In the initiation of translation in eukaryotes, binding of the small ribosomal subunit to the messenger RNA results from… 
Highly Cited
1998
Highly Cited
1998
IRP-1 binding to ferritin mRNA prevents the recruitment of the small ribosomal subunit by the cap-binding complex eIF4F.
Review
1997
Review
1997
Molecular mechanisms for the control of translation by insulin.
Insulin acutely stimulates protein synthesis in mammalian cells, and this involves activation of the process of mRNA translation… 
Highly Cited
1996
Highly Cited
1996
The C‐terminal domain of eukaryotic protein synthesis initiation factor (eIF) 4G is sufficient to support cap‐independent translation in the absence of eIF4E.
The foot and mouth disease virus, a picornavirus, encodes two forms of a cysteine proteinase (leader or L protease) that bisects… 
Review
1994
Review
1994
Translational control during heat shock.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)