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EIF4E wt Allele

Known as: EIF4E1, Eukaryotic Translation Initiation Factor 4E wt Allele, EIF4EL1 
Human EIF4E wild-type allele is located within 4q21-q25 and is approximately 59 kb in length. This allele, which encodes eukaryotic translation… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Deregulation of the phosphatidyl inositol trisphosphate kinase/AKT/mammalian target of rapamycin (mTOR) and RAS/mitogen-activated… Expand
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Highly Cited
2006
Highly Cited
2006
Hypoxia has recently been shown to activate the endoplasmic reticulum kinase PERK, leading to phosphorylation of eIF2alpha and… Expand
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Highly Cited
2002
Highly Cited
2002
To elucidate an outline of the mechanism of eukaryotic translation initiation, 48S complex formation was analyzed on defined… Expand
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Highly Cited
2001
Highly Cited
2001
Eukaryotic initiation factor (eIF) 4A is a DEAD box RNA helicase that works in conjunction with eIF4B, eIF4H, or as a subunit of… Expand
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Review
2001
Review
2001
Numerous reports established that in skeletal muscle the indispensable branched-chain amino acid leucine is unique in its ability… Expand
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Highly Cited
2001
Highly Cited
2001
All nuclear-encoded mRNAs contain a 5′ cap structure (m7GpppN, where N is any nucleotide), which is recognized by the eukaryotic… Expand
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Highly Cited
2000
Highly Cited
2000
We investigated the protein synthetic response of skeletal muscle to an orally administered dose of leucine given alone or in… Expand
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Highly Cited
1999
Highly Cited
1999
Although most eukaryotic mRNAs need a functional cap binding complex eIF4F for efficient 5' end- dependent scanning to initiate… Expand
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Highly Cited
1997
Highly Cited
1997
The cap structure, m7GpppN, is present at the 5′-end of all eukaryotic cellular (except organellar) mRNAs. Initiation of… Expand
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Highly Cited
1996
Highly Cited
1996
Translation of picornavirus RNA is initiated after ribosomal binding to an internal ribosomal entry site (IRES) within the 5… Expand
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