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Cytokine Signaling Process

Known as: Cytokine Activation 
Any process which promotes expression of cytokine proteins, their subsequent secretion, binding to their cognate receptors or intracellular signaling… Expand
National Institutes of Health

Related topics

Related topics

50 relations
ACKR1 geneACKR4 geneC-X-C Chemokine Receptor Type 1, humanC-X-C Chemokine Receptor Type 2, human
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Cytokine activation induces human memory-like NK cells.
Natural killer (NK) cells are lymphocytes that play an important role in the immune response to infection and malignancy. Recent… Expand
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Highly Cited
2008
Highly Cited
2008
Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
Caspase-1 cleaves the inactive IL-1β and IL-18 precursors into active inflammatory cytokines. In Salmonella-infected macrophages… Expand
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Review
2008
Review
2008
The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29.
Cytokines are involved in virtually every aspect of immunity and inflammation. A cascade of responses evolves after cytokine… Expand
Highly Cited
2005
Highly Cited
2005
Neuroglial activation and neuroinflammation in the brain of patients with autism
Autism is a neurodevelopmental disorder characterized by impaired communication and social interaction and may be accompanied by… Expand
Highly Cited
2002
Highly Cited
2002
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of…
OBJECTIVE Neonatal-onset multisystem inflammatory disease (NOMID; also known as chronic infantile neurologic, cutaneous… Expand
Highly Cited
2001
Highly Cited
2001
Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.
Naive CD4+ T cells activated through TCR/CD28 under Th1 or Th2 conditions expressed canonical cytokine patterns irrespective of… Expand
Review
2001
Review
2001
Pneumococcal Virulence Factors: Structure and Function
  • M. J. Jedrzejas
  • Microbiology and Molecular Biology Reviews
  • 2001
    • Corpus ID: 8371142
SUMMARY The overall goal for this review is to summarize the current body of knowledge about the structure and function of major… Expand
Highly Cited
1999
Highly Cited
1999
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation.
The suppressors of cytokine signaling (SOCS) family of proteins act as intracellular inhibitors of several cytokine signal… Expand
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Review
1997
Review
1997
Caspases: Intracellular Signaling by Proteolysis
The discovery of caspases has proceeded well ahead of our understanding of their place in the transmission of cellular… Expand
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Highly Cited
1995
Highly Cited
1995
Transcriptional Regulation of the Intercellular Adhesion Molecule-1 Gene by Inflammatory Cytokines in Human Endothelial Cells
Intercellular adhesion molecule-1 (ICAM-1) is greatly up-regulated on endothelial cells at sites of inflammation and is involved… Expand
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