Cytokine Signaling Process

Known as: Cytokine Activation 
Any process which promotes expression of cytokine proteins, their subsequent secretion, binding to their cognate receptors or intracellular signaling… (More)
National Institutes of Health

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ACKR1 geneACKR4 geneC-X-C Chemokine Receptor Type 1, humanC-X-C Chemokine Receptor Type 2, human
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Papers overview

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Highly Cited
2012
Highly Cited
2012
Cytokine activation induces human memory-like NK cells.
Natural killer (NK) cells are lymphocytes that play an important role in the immune response to infection and malignancy. Recent… (More)
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Highly Cited
2010
Highly Cited
2010
Delayed clearance of viral load and marked cytokine activation in severe cases of pandemic H1N1 2009 influenza virus infection.
BACKGROUND Infections caused by the pandemic H1N1 2009 influenza virus range from mild upper respiratory tract syndromes to fatal… (More)
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Highly Cited
2005
Highly Cited
2005
Neuroglial activation and neuroinflammation in the brain of patients with autism.
Autism is a neurodevelopmental disorder characterized by impaired communication and social interaction and may be accompanied by… (More)
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Highly Cited
2005
Highly Cited
2005
Acute inflammation and negative mood: Mediation by cytokine activation
Inflammatory diseases are commonly associated with depressed mood. This association may be influenced by the production of… (More)
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Highly Cited
2002
Highly Cited
2002
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of…
OBJECTIVE Neonatal-onset multisystem inflammatory disease (NOMID; also known as chronic infantile neurologic, cutaneous… (More)
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Highly Cited
2001
Highly Cited
2001
Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.
Naive CD4+ T cells activated through TCR/CD28 under Th1 or Th2 conditions expressed canonical cytokine patterns irrespective of… (More)
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Highly Cited
1999
Highly Cited
1999
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation.
The suppressors of cytokine signaling (SOCS) family of proteins act as intracellular inhibitors of several cytokine signal… (More)
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Highly Cited
1998
Highly Cited
1998
Cytokine activation leads to acidification and increases maturation of Mycobacterium avium-containing phagosomes in murine macrophages.
Mycobacterium avium (MAC) organisms multiply in phagosomes that have restricted fusigenicity with lysosomes, do not acidify due… (More)
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Highly Cited
1996
Highly Cited
1996
Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases.
Interleukin 1 (IL-1) and tumor necrosis factor alpha (TNFalpha) are known to induce production of reactive oxygen species (ROS… (More)
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Highly Cited
1995
Highly Cited
1995
Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kappa B site and p65 homodimers.
Intercellular adhesion molecule-1 (ICAM-1) is greatly up-regulated on endothelial cells at sites of inflammation and is involved… (More)
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