Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

C-X-C Chemokine Receptor Type 2, human

Known as: CDw128b, IL8RB, IL8 Receptor Type 2 
C-X-C chemokine receptor type 2 (360 aa, ~41 kDa) is encoded by the human CXCR2 gene. This protein plays a role in both chemokine binding and… Expand
National Institutes of Health

Related topics

Related topics

22 relations
CXCR2 geneChemokine Receptor GeneChemotaxisCytokine Receptor Gene
Expand

Broader (1)

Interleukin-8B Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
The cytokine macrophage migration inhibitory factor (MIF) plays a critical role in inflammatory diseases and atherogenesis. We… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2006
2006
Interleukin-8 secretion by fibroblasts induced by low density lipoproteins is p38 MAPK-dependent and leads to cell spreading and wound closure.
We have previously reported (Dobreva, I., Waeber, G., Mooser, V., James, R. W., and Widmann, C. (2003) J. Lipid Res. 44, 2382… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
In this study, we examined the biological action of IL-17 on human non-small cell lung cancer (NSCLC). Although IL-17 had no… Expand
  • figure 1
  • figure 2
  • figure 3
  • table I
  • figure 4
Is this relevant?
2003
2003
Association between interleukin-8 gene alleles and human susceptibility to tuberculosis disease.
Interleukin (IL)-8 is involved in the pathogenesis of human tuberculosis (TB). However, the contribution of polymorphisms of the… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells.
Ovarian cancer typically disseminates widely in the abdomen, a characteristic that limits curative therapy. The mechanisms that… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Distribution of novel polymorphisms of the interleukin-8 and CXC receptor 1 and 2 genes in systemic sclerosis and cryptogenic fibrosing alveolitis.
OBJECTIVE To search for single-nucleotide polymorphisms in the interleukin-8 (IL-8) and IL-8 receptor CXCR-1 and CXCR-2 genes… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice.
Chronic macrophage-mediated inflammation is central to atherosclerosis. A role of the monocyte chemotactic and activating C-C… Expand
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Endothelial cells differentially express functional CXC-chemokine receptor-4 (CXCR-4/fusin) under the control of autocrine activity and exogenous cytokines.
Analysis of endothelial cell (EC) chemokine receptor expression by RT-PCR revealed that EC essentially do not express CC… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Human vascular smooth muscle cells express receptors for CC chemokines.
Arteriosclerotic lesions are characterized by the accumulation of T lymphocytes and monocytes and the proliferation of intimal… Expand
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The murine homolog of the interleukin-8 receptor CXCR-2 is essential for the occurrence of neutrophilic inflammation in the air pouch model of acute urate crystal-induced gouty synovitis.
OBJECTIVE Acute neutrophil-dependent inflammation is central to acute gout. Urate crystals induce different classes of neutrophil… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE