Skip to search formSkip to main contentSkip to account menu

C-X-C Chemokine Receptor Type 2, human

Known as: CDw128b, IL8RB, IL8 Receptor Type 2 
C-X-C chemokine receptor type 2 (360 aa, ~41 kDa) is encoded by the human CXCR2 gene. This protein plays a role in both chemokine binding and… 
National Institutes of Health

Related topics

Related topics

22 relations
CXCR2 geneChemokine Receptor GeneChemotaxisCytokine Receptor Gene

Broader (1)

Interleukin-8B Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Cerebral ischemic damage in diabetes: an inflammatory perspective
Stroke is one of the leading causes of death worldwide. A strong inflammatory response characterized by activation and release of… 
Highly Cited
2010
Highly Cited
2010
STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction.
Neutrophil mobilization, the release of neutrophils from the bone marrow reserve into circulating blood, is important to increase… 
Highly Cited
2007
Highly Cited
2007
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
The cytokine macrophage migration inhibitory factor (MIF) plays a critical role in inflammatory diseases and atherogenesis. We… 
Highly Cited
2005
Highly Cited
2005
IL-17 Enhances the Net Angiogenic Activity and In Vivo Growth of Human Non-Small Cell Lung Cancer in SCID Mice through Promoting CXCR-2-Dependent Angiogenesis1
In this study, we examined the biological action of IL-17 on human non-small cell lung cancer (NSCLC). Although IL-17 had no… 
Highly Cited
2004
Highly Cited
2004
The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis.
Highly Cited
2000
Highly Cited
2000
Chemokine Receptors CXCR-1/2 Activate Mitogen-activated Protein Kinase via the Epidermal Growth Factor Receptor in Ovarian Cancer Cells*
Ovarian cancer typically disseminates widely in the abdomen, a characteristic that limits curative therapy. The mechanisms that… 
Highly Cited
1998
Highly Cited
1998
A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice.
Chronic macrophage-mediated inflammation is central to atherosclerosis. A role of the monocyte chemotactic and activating C-C… 
Highly Cited
1998
Highly Cited
1998
Human vascular smooth muscle cells express receptors for CC chemokines.
Arteriosclerotic lesions are characterized by the accumulation of T lymphocytes and monocytes and the proliferation of intimal… 
Highly Cited
1998
Highly Cited
1998
Endothelial cells differentially express functional CXC-chemokine receptor-4 (CXCR-4/fusin) under the control of autocrine activity and exogenous cytokines.
Analysis of endothelial cell (EC) chemokine receptor expression by RT-PCR revealed that EC essentially do not express CC… 
Highly Cited
1992
Highly Cited
1992
Molecular evolution of the human interleukin–8 receptor gene cluster
Abstractlnterleukin–8 (IL–8) is the prototype for a family of at least eight neutrophil chemoattractants whose genes map to human… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License