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EIF4E gene

Known as: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EIF4E-LIKE 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E FAMILY, MEMBER 1 
This gene is involved in translation initiation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Hyperconnectivity of neuronal circuits due to increased synaptic protein synthesis is thought to cause autism spectrum disorders… Expand
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Highly Cited
2010
Highly Cited
2010
We genetically dissect the contribution of the most prominent downstream translational components of mTOR signaling toward Akt… Expand
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Highly Cited
2007
Highly Cited
2007
Assembly of the eIF4E/eIF4G complex has a central role in the regulation of gene expression at the level of translation… Expand
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Highly Cited
2007
Highly Cited
2007
Regulation of protein synthesis is critical for cell growth and maintenance. Ageing in many organisms, including humans, is… Expand
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Highly Cited
2006
Highly Cited
2006
This study demonstrates that the eukaryotic translation initiation factor eIF4E is a critical node in an RNA regulon that impacts… Expand
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Highly Cited
2004
Highly Cited
2004
Evading apoptosis is considered to be a hallmark of cancer, because mutations in apoptotic regulators invariably accompany… Expand
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Highly Cited
2004
Highly Cited
2004
Although the activity of the translation initiation factor eIF4F is regulated in part by translational repressors (4E-BPs) that… Expand
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Highly Cited
2004
Highly Cited
2004
Translational regulation plays an essential role in development and often involves factors that interact with sequences in the 3… Expand
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Highly Cited
2004
Highly Cited
2004
The eukaryotic translation initiation factor eIF4E is dysregulated in a wide variety of human cancers. In the cytoplasm, eIF4E… Expand
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Highly Cited
2003
Highly Cited
2003
The eukaryotic initiation factor 4G (eIF4G) is the core of a multicomponent switch controlling gene expression at the level of… Expand
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