Skip to search formSkip to main contentSkip to account menu

EIF4E gene

Known as: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EIF4E-LIKE 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E FAMILY, MEMBER 1 
This gene is involved in translation initiation.
National Institutes of Health

Related topics

Related topics

9 relations
Cytokine Signaling ProcessEukaryotic Initiation Factor-4EEukaryotic Translation Initiation Factor 4E, humanGenetic Translation Process

Narrower (1)

EIF4E wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Expression analysis and clinical significance of eIF4E, VEGF-C, E-cadherin and MMP-2 in colorectal adenocarcinoma
The underlying mechanisms of colorectal carcinoma (CRC) metastasis remain to be elucidated. The aim of this study is to… 
2014
2014
PRMT5 is essential for the eIF4E-mediated 5'-cap dependent translation.
2012
2012
Cryptotanshinone induces cell cycle arrest and apoptosis of multidrug resistant human chronic myeloid leukemia cells by inhibiting the activity of eukaryotic initiation factor 4E
Cryptotanshinone (CPT), a diterpene quinone isolated from Salvia miltiorrhiza, is recently reported to have obvious anticancer… 
Highly Cited
2009
Highly Cited
2009
Inhibition of Ovarian Cancer Growth by a Tumor-Targeting Peptide That Binds Eukaryotic Translation Initiation Factor 4E
Purpose: A critical step of protein synthesis involves the liberation of the mRNA cap-binding translation initiation factor eIF4E… 
2008
2008
Vesicular Stomatitis Virus Oncolysis of T Lymphocytes Requires Cell Cycle Entry and Translation Initiation
ABSTRACT Vesicular stomatitis virus (VSV) is a candidate oncolytic virus that replicates and induces cell death in cancer cells… 
Highly Cited
2007
Highly Cited
2007
Expression levels of eIF4E, VEGF, and cyclin D1, and correlation of eIF4E with VEGF and cyclin D1 in multi-tumor tissue microarray.
The mRNA cap-binding protein, eukaryotic initiation factor 4E (eIF4E), is a rate-limiting factor of cap-dependent translation… 
Highly Cited
2001
Highly Cited
2001
Possible mechanisms involved in the down-regulation of translation during transient global ischaemia in the rat brain.
The striking correlation between neuronal vulnerability and down-regulation of translation suggests that this cellular process… 
2000
2000
Plant lipoxygenase 2 is a translation initiation factor-4E-binding protein
The eukaryotic initiation factor 4E (eIF4E) emerged recently as a target for different types of regulation affecting translation… 
1999
1999
Differential expression of Myc1 and Myc2 isoforms in cells transformed by eIF4E: evidence for internal ribosome repositioning in the human c-myc 5′UTR
eIF4E is essential for translation initiation, but its overexpression causes malignant transformation. Recent work demonstrated… 
1998
1998
Detection of eIF4E gene amplification in breast cancer by competitive PCR
AbstractBackground: Initiation factor eIF4E binds to mRNA as the initial step for protein translation. Overexpression of the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)