EIF4E gene

Known as: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EIF4E-LIKE 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E FAMILY, MEMBER 1 
This gene is involved in translation initiation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2018
020406019912018

Papers overview

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Highly Cited
2009
Highly Cited
2009
The eukaryotic translation initiation factor eIF4E is elevated in 30% of malignancies including M4/M5 subtypes of acute myeloid… (More)
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Highly Cited
2007
Highly Cited
2007
Genetically engineered mouse models are powerful tools for studying cancer genes and validating targets for cancer therapy. We… (More)
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Highly Cited
2007
Highly Cited
2007
Assembly of the eIF4E/eIF4G complex has a central role in the regulation of gene expression at the level of translation… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Translation deregulation is an important mechanism that causes aberrant cell growth, proliferation and survival. eIF4E… (More)
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Highly Cited
2006
Highly Cited
2006
This study demonstrates that the eukaryotic translation initiation factor eIF4E is a critical node in an RNA regulon that impacts… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in the eIF4E homolog encoded at the pvr1 locus in Capsicum result in broad-spectrum potyvirus resistance attributed to… (More)
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Highly Cited
2004
Highly Cited
2004
The mammalian target of rapamycin (mTOR) integrates nutrient and mitogen signals to regulate cell growth (increased cell mass and… (More)
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Highly Cited
2004
Highly Cited
2004
From the characterization of the recessive resistance gene, sbm1, in pea we have identified the eukaryotic translation initiation… (More)
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Highly Cited
2002
Highly Cited
2002
We show here that the pvr2 locus in pepper, conferring recessive resistance against strains of potato virus Y (PVY), corresponds… (More)
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Highly Cited
2002
Highly Cited
2002
The coordinated action of cell cycle progression and cell growth (an increase in cell size and cell mass) is critical for… (More)
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