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Eukaryotic Initiation Factor-4E

Known as: Eukaryotic Peptide Initiation Factor 4E, CDC33 Gene Product, Eukaryotic Initiation Factor-4E [Chemical/Ingredient] 
A peptide initiation factor that binds specifically to the 5' MRNA CAP STRUCTURE of MRNA in the CYTOPLASM. It is a component of the trimeric complex… 
National Institutes of Health

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EIF4E geneIn BloodProcess of secretionagonists

Papers overview

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2019
2019
The eukaryotic initiation factor 4E (eIF4E) as a predictive biomarker in the negative margins of resected head and neck and oral cancers: Is there a role for tailoring adjuvant radiotherapy
Introduction: The eukaryotic translation initiation factor 4E (eIF4E) is a protein that plays a key role in the tumourigenesis… 
2014
2014
Cell Death and Survival mTOR Inhibition Potentiates HSP 90 Inhibitor Activity via Cessation of HSP Synthesis
Because of their pleiotropic effects on critical oncoproteins, inhibitors of HSP90 represent a promising new class of therapeutic… 
2013
2013
Cooperative modulation by eIF 4 G of eIF 4 E-binding to the mRNA 5 cap in yeast involves a site partially shared by p 20
Interaction between the mRNA 5 -cap-binding protein eIF4E and the multiadaptor protein eIF4G has been demonstrated in all… 
2013
2013
Association of maternal mRNA and phosphorylated EIF 4 EBP 1 variants with the 1 spindle in mouse oocytes : localized translational control supporting female 2 meiosis in mammals 3 4
51 52 53 The oocytes of many species, both invertebrate and vertebrate, contain a large 54 collection of localized determinants… 
2012
2012
mTOR inhibitor efficacy is determined by the eIF4E/4E-BP ratio
The mammalian/mechanistic target of rapamycin (mTOR) is a multifunctional serine/threonine kinase that is hyperactivated in… 
2012
2012
Therapeutics , Targets , and Chemical Biology Translation Initiation Factor eIF 4 E Is a Target for Tumor Cell Radiosensitization
A core component in the cellular response to radiation occurs at the level of translational control of gene expression. Because a… 
2011
2011
Nuevas herramientas en la lucha contra las virosis del pimiento
Las enfermedades de etiologia viral destacan por ser el principal factor limitante de las hortalizas. La estrategia mas eficaz… 
2006
2006
eIF4E exports proliferation mRNAs
![Graphic][1] eIF4E (green) exports transcripts with a particular stem loop structure (red), but PML (blue) interferes with… 
2001
2001
Transformation of Cloned Rat Embryo Fibroblasts Results in Increased Rates of Protein Synthesis and Phosphorylation of Eukaryotic Initiation Factor 4 E *
Eukaryotic initiation factor 4E (eIF-4E) is a 25-kDa phosphoprotein that binds to the 7-methylguanosine cap of mRNA and acts… 
1999
1999
Chronic alcohol feeding impairs hepatic translation initiation by modulating eIF 2 and eIF 4 E
Lang, Charles H., Duanqing Wu, Robert A. Frost, Leonard S. Jefferson, Thomas C. Vary, and Scot R. Kimball. Chronic alcohol… 
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