Eukaryotic Initiation Factor-4E

Known as: Eukaryotic Peptide Initiation Factor 4E, CDC33 Gene Product, Eukaryotic Initiation Factor-4E [Chemical/Ingredient] 
A peptide initiation factor that binds specifically to the 5' MRNA CAP STRUCTURE of MRNA in the CYTOPLASM. It is a component of the trimeric complex… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
05101519852017

Papers overview

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2009
2009
The eukaryotic translation initiation factor 4E (eIF4E) controls gene expression through its effects on mRNA export and cap… (More)
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Highly Cited
1998
Highly Cited
1998
The present study identifies the operation of a signal tranduction pathway in mammalian cells that provides a checkpoint control… (More)
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Highly Cited
1996
Highly Cited
1996
The structure of m7GpppN (where N is any nucleotide), termed cap, is present at the 5' end of all eukaryotic cellular mRNAs… (More)
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Highly Cited
1995
Highly Cited
1995
Regulation of the cell cycle is orchestrated by cyclins and cyclin-dependent kinases. We have demonstrated previously that… (More)
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1995
1995
Suppression of protein synthesis in the brain following an ischemic insult has been thought to occur because of inhibition of… (More)
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Highly Cited
1994
Highly Cited
1994
Eukaryotic translation initiation factor eIF-4E plays a central role in the recognition of the 7-methylguanosine-containing cap… (More)
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Highly Cited
1993
Highly Cited
1993
Cyclin D1 is a G1-specific cyclin that has been linked to lymphoid, parathyroid, and breast tumors. Recent studies suggested that… (More)
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Highly Cited
1992
Highly Cited
1992
Cellular eukaryotic mRNAs (except organellar) contain at the 5' terminus the structure m7(5')Gppp(5')N (where N is any nucleotide… (More)
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Highly Cited
1992
Highly Cited
1992
The 5' cap structure m7GpppN (where N is any nucleotide) is a ubiquitous feature of cellular eukaryotic mRNAs. The cap is… (More)
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Highly Cited
1990
Highly Cited
1990
Eukaryotic protein synthesis initiation factor 4E (eIF-4E) is a 25-kDa polypeptide that binds to the 7-methylguanosine-containing… (More)
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