Eukaryotic Translation Initiation Factor 4E, human

Known as: eIF4E, eIF-4F 25 kDa Subunit, eIF-4E 
Eukaryotic translation initiation factor 4E (217 aa, ~25 kDa) is encoded by the human EIF4E gene. This protein is involved in the initiation of mRNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2017
05010019822017

Papers overview

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Highly Cited
2011
Highly Cited
2011
The PI3K pathway is frequently activated in cancer; therefore, considerable effort is focused on identifying compounds that can… (More)
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2008
2008
Despite their self-sufficient ability to generate capped mRNAs from cytosolic DNA genomes, poxviruses must commandeer the… (More)
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Highly Cited
2007
Highly Cited
2007
Metformin is used for the treatment of type 2 diabetes because of its ability to lower blood glucose. The effects of metformin… (More)
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Highly Cited
2007
Highly Cited
2007
Assembly of the eIF4E/eIF4G complex has a central role in the regulation of gene expression at the level of translation… (More)
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Highly Cited
2003
Highly Cited
2003
The eukaryotic translation initiation factor 4E (eIF4E) acts as both a key translation factor and as a promoter of… (More)
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Highly Cited
2003
Highly Cited
2003
The eIF4E and eIF(iso)4E cDNAs from several genotypes of lettuce (Lactuca sativa) that are susceptible, tolerant, or resistant to… (More)
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Highly Cited
1999
Highly Cited
1999
Human eukaryotic translation initiation factor 4E (eIF4E) binds to the mRNA cap structure and interacts with eIF4G, which serves… (More)
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Highly Cited
1999
Highly Cited
1999
Eukaryotic translation initiation factor 4E (eIF4E) binds to the mRNA 5' cap and brings the mRNA into a complex with other… (More)
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Highly Cited
1999
Highly Cited
1999
The multisubunit eukaryotic translation initiation factor (eIF) 4F recruits 40S ribosomal subunits to the 5' end of mRNA. The… (More)
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Highly Cited
1995
Highly Cited
1995
Eukaryotic translation initiation factor 4E (eIF-4E), which possesses cap-binding activity, functions in the recruitment of mRNA… (More)
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