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Pentostatin

Known as: 2' Deoxycoformycin, Pentostatinum, DCF 
A purine nucleotide analogue antibiotic isolated from the bacterium Streptomyces antibioticus. Also known as 2'-deoxycoformycin, pentostatin binds to… 
National Institutes of Health

Related topics

Related topics

31 relations

Narrower (6)

2'-deoxycoformycin 5'-phosphate8-ketodeoxycoformycinCo-VidarabineNSC-218321
ADENOSINE DEAMINASEDrug AllergyHairy Cell LeukemiaIn Blood

Broader (7)

Adenosine Deaminase InhibitorsAntibiotics, AntineoplasticAntineoplastic AgentsFormycins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Single-walled carbon nanotubes induces oxidative stress in rat lung epithelial cells.
Single-walled carbon nanotubes (SWCNT) show unique properties find applications in micro devices; electronics to biological… 
Highly Cited
2002
Highly Cited
2002
Bicarbonate Enhances Peroxidase Activity of Cu,Zn-Superoxide Dismutase
Much evidence exists for the increased peroxidase activity of copper, zinc superoxide dismutase (SOD1) in oxidant-induced… 
Highly Cited
2000
Highly Cited
2000
Microchip devices for high-efficiency separations.
We have fabricated a 25-cm-long spiral-shaped separation channel on a glass microchip with a footprint of only 5 cm x 5 cm… 
Highly Cited
1988
Highly Cited
1988
Identification of adducts formed by reaction of guanine nucleosides with malondialdehyde and structurally related aldehydes.
Malondialdehyde and a series of acrolein derivatives substituted in the beta-position with good leaving groups react with guanine… 
Highly Cited
1987
Highly Cited
1987
D‐erythro‐neopterin plasma levels in intensive care patients with and without septic complications
The activation of macrophages is accompanied by release of 2-amino-4-oxo-6(D-erythro-l′,2′,3′-trihy-droxypropyl)-dihydropteridine… 
Highly Cited
1983
Highly Cited
1983
An investigation of 2'-deoxycoformycin in the treatment of cutaneous T-cell lymphoma.
We have investigated the use of 2'-deoxycoformycin (DCF), a potent inhibitor of adenosine deaminase (ADA), in the treatment of 4… 
Highly Cited
1979
Highly Cited
1979
An enzyme-linked immunosorbent assay for detecting avian leukosis-sarcoma viruses.
Immunoglobulins from antiserum raised against chromatographically purified avian myeloblastosis virus (AMV) group-specific (gs… 
Highly Cited
1979
Highly Cited
1979
Adenosine modulation of synaptosomal dopamine release.
Highly Cited
1977
Highly Cited
1977
Specificity of adenosine deaminase inhibitors.
Highly Cited
1976
Highly Cited
1976
Enhancement of the antitumor activity of arabinofuranosyladenine of 2'-deoxycoformycin.
The 6C3HED lymphosarcoma, a tumor cell line very sensitive to 9-beta-D-arabinofuranosyladenine (ara-A), and 6C3HED/ara-A, a line… 
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