Skip to search formSkip to main contentSkip to account menu

ADENOSINE DEAMINASE

Known as: Adenosine aminohydrolase, Adenosine Deaminase [Chemical/Ingredient], Aminohydrolase, Adenosine 
Adenosine deaminase (363 aa, ~41 kDa) is encoded by the human ADA gene. This protein plays a role in purine metabolism.
National Institutes of Health

Related topics

Related topics

27 relations
ADA geneADCP1 geneAdenine deaminaseAdenosine deaminase binding protein:MCnc:Pt:Urine:Qn

Broader (1)

Aminohydrolases

Narrower (5)

Severe combined immunodeficiency due to adenosine deaminase deficiencyTadA protein, E coliadenosine deaminase activityadenosine deaminase-complexing protein, Oryctolagus cuniculus

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Adenosine-Dependent Pulmonary Fibrosis in Adenosine Deaminase-Deficient Mice1
Pulmonary fibrosis is a common feature of numerous lung disorders, including interstitial lung diseases, asthma, and chronic… 
Highly Cited
2002
Highly Cited
2002
Luminal Ca2+ Controls Termination and Refractory Behavior of Ca2+-Induced Ca2+ Release in Cardiac Myocytes
Abstract— Despite extensive research, the mechanisms responsible for the graded nature and early termination of Ca2+-induced Ca2… 
Review
1999
Review
1999
Bioconjugation in pharmaceutical chemistry.
Highly Cited
1999
Highly Cited
1999
Analysis of the Critical Domain in the V3 Loop of Human Immunodeficiency Virus Type 1 gp120 Involved in CCR5 Utilization
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) infection of CD4+ lymphocytes and macrophages involves interaction of the… 
Highly Cited
1998
Highly Cited
1998
Amino-Terminal Substitutions in the CCR5 Coreceptor Impair gp120 Binding and Human Immunodeficiency Virus Type 1 Entry
ABSTRACT The CC-chemokine receptor CCR5 is required for the efficient fusion of macrophage (M)-tropic human immunodeficiency… 
Highly Cited
1992
Highly Cited
1992
Serum adenosine deaminase: isoenzymes and diagnostic application.
Human adenosine deaminase (ADA; EC 3.5.4.4) consists of three isoenzymes: ADA1, ADA1+CP, and ADA2. We developed an… 
Highly Cited
1992
Highly Cited
1992
ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line.
Highly Cited
1977
Highly Cited
1977
Human adenosine deaminase. Purification and subunit structure.
Human erythrocyte adenosine deaminase has been purified approximately 800,000-fold to apparent homogeneity using antibody… 
Highly Cited
1977
Highly Cited
1977
Hereditary hemolytic anemia with increased red cell adenosine deaminase (45- to 70-fold) and decreased adenosine triphosphate.
Hereditary hemolytic anemia, a dominantly transmitted disorder, has affected 12 family members spanning three generations. The… 
Review
1969
Review
1969
Further data on the adenosine deaminase (ADA) polymorphism and a report of a new phenotype
In a study of human red cell adenosine deaminase (ADA) three different types of isozyme patterns were identified (Spencer… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)