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ADA gene
Known as:
Adenosine Deaminase Gene
, ADENOSINE AMINOHYDROLASE
, ADENOSINE DEAMINASE
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This gene is involved in nucleotide metabolism and cellular immunity.
National Institutes of Health
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Related topics
Related topics
5 relations
ADENOSINE DEAMINASE
Hydrolysis
Nucleotide Metabolism
Severe Combined Immunodeficiency
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Integrase-defective lentiviral vectors as a delivery platform for targeted modification of adenosine deaminase locus.
Alok V. Joglekar
,
R. Hollis
,
G. Kuftinec
,
S. Senadheera
,
R. Chan
,
D. Kohn
Molecular Therapy
2013
Corpus ID: 43585749
We investigated the use of integrase-defective lentiviral vectors (IDLVs) for transient delivery of zinc finger nucleases (ZFNs…
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2007
2007
ADA*2 Allele of the Adenosine Deaminase Gene May Protect against Coronary Artery Disease
K. Safranow
,
R. Rzeuski
,
+8 authors
D. Chlubek
The Cardiology
2007
Corpus ID: 37412734
Background/Aims: The common G22A polymorphism in the adenosine deaminase (ADA) gene leads to substitution Asp8Asn. The lower…
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Highly Cited
1995
Highly Cited
1995
The interferon-inducible, double-stranded RNA-specific adenosine deaminase gene (DSRAD) maps to human chromosome 1q21.1-21.2.
H. Weier
,
C. George
,
K. Greulich
,
C. E. Samuel
Genomics
1995
Corpus ID: 27926644
The interferon-inducible double-stranded RNA-specific adenosine deaminase is an RNA-modifying enzyme implicated in the generation…
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Highly Cited
1992
Highly Cited
1992
Transcription affects the rate but not the extent of repair of cyclobutane pyrimidine dimers in the human adenosine deaminase gene.
J. Venema
,
Z. Bartosova
,
A. Natarajan
,
A. V. van Zeeland
,
L. Mullenders
Journal of Biological Chemistry
1992
Corpus ID: 25747071
1990
1990
Identification of transcription stop sites at the 5' and 3' ends of the murine adenosine deaminase gene.
M. Maa
,
J. Chinsky
,
V. Ramamurthy
,
B. D. Martin
,
R. Kellems
Journal of Biological Chemistry
1990
Corpus ID: 28768124
1986
1986
Genetic heterogeneity in adenosine deaminase (ADA) deficiency: five different mutations in five new patients with partial ADA deficiency.
R. Hirschhorni
,
A. Ellenbogen
American Journal of Human Genetics
1986
Corpus ID: 28998334
Complete genetic deficiency of adenosine deaminase (ADA) results in a fatal syndrome of severe combined immunodeficiency (SCID…
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Highly Cited
1983
Highly Cited
1983
Selective overproduction of adenosine deaminase in cultured mouse cells.
C. Yeung
,
D. Ingolia
,
+4 authors
R. Kellems
Journal of Biological Chemistry
1983
Corpus ID: 1965596
The objective of this work was to isolate cultured mouse cells with amplified adenosine deaminase genes. Such cell lines should…
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Highly Cited
1983
Highly Cited
1983
Molecular cloning of human adenosine deaminase gene sequences.
S. Orkin
,
P. Daddona
,
+4 authors
W. Kelley
Journal of Biological Chemistry
1983
Corpus ID: 1294557
1983
1983
Amplification and molecular cloning of murine adenosine deaminase gene sequences.
C. Yeung
,
E. Frayne
,
+4 authors
R. Kellems
Journal of Biological Chemistry
1983
Corpus ID: 35870570
Highly Cited
1974
Highly Cited
1974
Molecular form of adenosine deaminase in severe combined immunodeficiency.
M. van der Weyden
,
R. Buckley
,
W. Kelley
Biochemical and Biophysical Research…
1974
Corpus ID: 21864851
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