ADA gene

Known as: Adenosine Deaminase Gene, ADENOSINE AMINOHYDROLASE, ADENOSINE DEAMINASE 
This gene is involved in nucleotide metabolism and cellular immunity.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2016
051019692016

Papers overview

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2011
2011
The relative frequency of the different forms of SCID may vary in different countries. The most frequent form in Israel is the… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND We investigated the long-term outcome of gene therapy for severe combined immunodeficiency (SCID) due to the lack of… (More)
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2006
2006
Using a mouse model of adenosine deaminase-deficient severe combined immune deficiency syndrome (ADA-deficient SCID), we have… (More)
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2006
2006
Adenosine deaminase (ADA) deficiency is caused by a purine metabolic dysfunction, leading to severe combined immunodeficiency… (More)
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1999
1999
Adenosine deaminase (ADA) gene expression is induced by 17beta-estradiol (E2) in MCF-7 human breast cancer cells, whereas the… (More)
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Highly Cited
1998
Highly Cited
1998
Adenosine deaminase-deficient severe combined immunodeficiency was the first disease investigated for gene therapy because of a… (More)
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1997
1997
The ADA genes encode factors which are proposed to function as transcriptional coactivators. Here we describe the cloning… (More)
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1996
1996
Adenosine deaminase (ADA) deficiency results in severe combined immune deficiency disease (SCID), which is fatal without… (More)
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1991
1991
We have measured the removal of UV-induced pyrimidine dimers from DNA fragments of the adenosine deaminase (ADA) and… (More)
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1990
1990
  • Human gene therapy
  • 1990
Severe combined immunodeficiency (SCID) due to deficiency of the purine metabolic enzyme adenosine deaminase (ADA) is a fatal… (More)
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