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Severe Combined Immunodeficiency

Known as: severe combined immunodeficiency disease, Immunodeficiency Syndrome, Severe Combined, combined immunodeficiency severe 
A rare, inherited disease that is marked by a lack of B lymphocytes (white blood cells that make antibodies and help fight infections) and a lack of… 
National Institutes of Health

Related topics

Related topics

46 relations
ADA geneADENOSINE DEAMINASEAdenosine deaminase deficiencyBare Lymphocyte Syndrome

Narrower (11)

AGAMMAGLOBULINEMIA, LYMPHOPENICBare lymphocyte syndrome 2Immune dysfunction with T-cell inactivation due to calcium entry defect 2Omenn Syndrome

Broader (2)

Immunologic Deficiency Syndromesinborn immunodeficiency

Papers overview

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Highly Cited
2003
Highly Cited
2003
Validez interna y utilidad diagnóstica del Eating Disorders Inventory en mujeres mexicanas
OBJETIVO: Determinar la utilidad diagnostica y la validez interna del Eating Disorder Inventory (EDI-2) en mujeres mexicanas… 
1995
1995
Characterization of B-cell lines established from two X-linked severe combined immunodeficiency patients: interleukin-15 binds to the B cells but is not internalized efficiently.
X-linked severe combined immunodeficiency (XSCID) is characterized by absent or profoundly reduced numbers of T cells and normal… 
Review
1991
Review
1991
Humoral Immunity in scid Mice Reconstituted with Cells from Immunoglobulin‐Deficient or Normal Humans
The complexity of the immune system makes it difficult to study the influence of genetic variation in humans by the use of… 
Highly Cited
1986
Highly Cited
1986
Full reconstitution of the immune deficiency in scid mice with normal stem cells requires low-dose irradiation of the recipients.
Mice homozygous for an autosomal recessive mutation for the scid gene exhibit a defect that specifically impairs lymphoid… 
1986
1986
An expanded population of natural killer cells in mice with severe combined immunodeficiency (SCID) lack rearrangement and expression of T cell receptor genes
Mice with severe combined immunodeficiency syndrome (SCID) exhibit an impairment in both T and B cell maturation, whereas… 
Highly Cited
1985
Highly Cited
1985
The function of antigen-presenting cells in mice with severe combined immunodeficiency.
We have examined the antigen-presenting function of spleen cells in the C.B-17 scid mouse, a mutation that severely impairs the… 
1984
1984
Prenatal diagnosis of three cases of severe combined immunodeficiency: severe T cell deficiency during the first half of gestation in fetuses with adenosine deaminase deficiency.
The prenatal diagnosis of severe combined immunodeficiency (SCID) was made in three fetuses by staining fetal blood obtained at… 
1983
1983
Demonstration of abnormalities in expression of thymic epithelial surface antigens in severe cellular immunodeficiency diseases.
Thymic epithelium from three patients with severe cellular immunodeficiency diseases were compared with age-matched normal thymic… 
Highly Cited
1976
Highly Cited
1976
Heterogeneity of lymphocyte subpopulations in severe combined immunodeficiency. Evidence against a stem cell defect.
Surface markers typical of T and B lymphocytes were present on varying proportions of peripheral blood lymphocytes from three… 
1972
1972
An immunological study during post-transplantation follow-up of a case of severe combined immunodeficiency.
A 5-month-old boy with severe combined immunodeficiency treated 2 years ago by transplantation of a foetal thymus and bone marrow…