Severe Combined Immunodeficiency

Known as: severe combined immunodeficiency disease, Immunodeficiency Syndrome, Severe Combined, combined immunodeficiency severe 
A rare, inherited disease that is marked by a lack of B lymphocytes (white blood cells that make antibodies and help fight infections) and a lack of… (More)

Topic mentions per year

Topic mentions per year

1971-2017
010020019712017

Papers overview

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Highly Cited
2004
Highly Cited
2004
BACKGROUND X-linked severe combined immunodeficiency (SCID-X1) is caused by mutations in the common cytokine-receptor gamma chain… (More)
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Highly Cited
2003
Highly Cited
2003
to the editor: We recently reported (April 18 issue) 1 the sustained correction of X-linked severe combined immunodeficiency… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND X-linked severe combined immunodeficiency due to a mutation in the gene encoding the common gamma (gamma(c)) chain is… (More)
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Highly Cited
2000
Highly Cited
2000
Severe combined immunodeficiency-X1 (SCID-X1) is an X-linked inherited disorder characterized by an early block in T and natural… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Since 1968 it has been known that bone marrow transplantation can ameliorate severe combined immunodeficiency, but… (More)
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Highly Cited
1998
Highly Cited
1998
Severe combined immunodeficiency (SCID) is caused by multiple genetic defects. The most common form of SCID, X-linked SCID (XSCID… (More)
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Highly Cited
1994
Highly Cited
1994
A homozygous mutation in the kinase domain of ZAP-70, a T cell receptor-associated protein tyrosine kinase, produced a… (More)
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Highly Cited
1993
Highly Cited
1993
The interleukin-2 (IL-2) receptor gamma chain (IL-2R gamma) is a component of high and intermediate affinity IL-2 receptors that… (More)
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Highly Cited
1988
Highly Cited
1988
The pressing need for a better experimental system for AIDS research has brought into sharp focus the shortcomings of available… (More)
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Highly Cited
1983
Highly Cited
1983
The most debilitating human lymphoid deficiency disease, known as severe combined immunodeficiency (SCID), impairs the… (More)
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