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Severe Combined Immunodeficiency
Known as:
severe combined immunodeficiency disease
, Immunodeficiency Syndrome, Severe Combined
, combined immunodeficiency severe
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A rare, inherited disease that is marked by a lack of B lymphocytes (white blood cells that make antibodies and help fight infections) and a lack of…
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National Institutes of Health
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Related topics
Related topics
46 relations
ADA gene
ADENOSINE DEAMINASE
Adenosine deaminase deficiency
Bare Lymphocyte Syndrome
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Narrower (11)
AGAMMAGLOBULINEMIA, LYMPHOPENIC
Bare lymphocyte syndrome 2
Immune dysfunction with T-cell inactivation due to calcium entry defect 2
Omenn Syndrome
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Broader (2)
Immunologic Deficiency Syndromes
inborn immunodeficiency
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Immune deficiencies , infection , and systemic immune disorders Transplantation of hematopoietic stem cells and long-term survival for primary immunodeficiencies in Europe : Entering a new century…
A. Gennery
,
M. Slatter
,
+22 authors
P. Landais
2010
Corpus ID: 33697760
Andrew R. Gennery, MD,* Mary A. Slatter, MD,* Laure Grandin, MSc, Pierre Taupin, MD, Andrew J. Cant, FRCP, Paul Veys, FRCP…
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Highly Cited
2007
Highly Cited
2007
Gene therapy improves immune function in preadolescents with X-linked severe combined immunodeficiency.
J. Chinen
,
Joie N. Davis
,
+10 authors
J. Puck
Blood
2007
Corpus ID: 7465849
Retroviral gene therapy can restore immunity to infants with X-linked severe combined immunodeficiency (XSCID) caused by…
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Highly Cited
2003
Highly Cited
2003
Characterization of ARC-111 as a novel topoisomerase I-targeting anticancer drug.
Tsai-Kun Li
,
P. Houghton
,
+6 authors
Leroy F. Liu
Cancer Research
2003
Corpus ID: 10259216
8,9-Dimethoxy-5-(2-N,N-dimethylaminoethyl)-2,3-methylenedioxy-5H-dibenzo[c,h][1,6] naphthyridin-6-one (ARC-111, topovale) is a…
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Highly Cited
2000
Highly Cited
2000
Performance Evaluation of a Combined Input- and Crosspoint-Queued Switch
M. Nabeshima
2000
Corpus ID: 5683787
This letter proposes a combined inputand crosspoint-queued (CIC) switch in which virtual output queuing (VOQ) is used at each…
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Highly Cited
1998
Highly Cited
1998
Enterohepatic lesions in SCID mice infected with Helicobacter bilis.
C. Franklin
,
L. Riley
,
R. Livingston
,
C. S. Beckwith
,
C. Besch-Williford
,
R. Hook
Laboratory animal science
1998
Corpus ID: 9949766
Helicobacter bilis is a recently identified species that colonizes the intestine and liver of mice. In immunocompetent mice…
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Highly Cited
1996
Highly Cited
1996
Retroviral-mediated gene correction for X-linked severe combined immunodeficiency.
F. Candotti
,
James A. Johnston
,
J. M. Puck
,
Kazuo Sugamura
,
John J. OShea
,
R. Blaese
Blood
1996
Corpus ID: 8944603
X-linked severe combined immunodeficiency (XSCID) is a lethal disease caused by a defect in the gene encoding the common gamma…
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Highly Cited
1994
Highly Cited
1994
Intracerebral cytokine mRNA expression during fatal and nonfatal alphavirus encephalitis suggests a predominant type 2 T cell response.
S. Wesselingh
,
Elizabeth Levine
,
Robin Fox
,
Seungjin Choi
,
Diane E. Griffin
Journal of Immunology
1994
Corpus ID: 24593317
Sindbis virus (SV) causes an acute encephalomyelitis in mice. A T cell-dependent inflammatory response is first detected 3 days…
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Review
1994
Review
1994
Bone marrow transplantation (BMT) in Europe for primary immunodeficiencies other than severe combined immunodeficiency: a report from the European Group for BMT and the European Group for…
A. Fischer
,
P. Landais
,
+7 authors
M. Cavazzana‐Calvo
1994
Corpus ID: 208294504
Bone marrow (BM) transplantations performed between 1977 and 1991 at 13 European centers in 149 patients with 11 different…
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Highly Cited
1989
Highly Cited
1989
Growth of human tumors in immune-deficient scid mice and nude mice.
R. A. Phillips
,
M. Jewett
,
B. Gallie
Current Topics in Microbiology and Immunology
1989
Corpus ID: 43601467
The ability to grow human tumors in immune-deficient mice offers offers many research opportunities (Sharkey and Fogh 1984). In…
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Highly Cited
1985
Highly Cited
1985
The function of antigen-presenting cells in mice with severe combined immunodeficiency.
A. Czitrom
,
S. Edwards
,
R. A. Phillips
,
M. Bosma
,
P. Marrack
,
J. Kappler
Journal of Immunology
1985
Corpus ID: 9314812
We have examined the antigen-presenting function of spleen cells in the C.B-17 scid mouse, a mutation that severely impairs the…
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