Skip to search formSkip to main contentSkip to account menu

Adenosine Deaminase Inhibitors

Known as: ADA Inhibitors, ADA Inhibitor, Inhibitors, Adenosine Deaminase 
Any substance that inhibits adenosine deaminase, an enzyme involved with the degradation of adenine in purine metabolism and that acts as a positive… 
National Institutes of Health

Related topics

Related topics

9 relations

Narrower (4)

5-(formylamino)imidazole ribosidePentostatinadechlorinadecypenol
Adenosine Deaminase Inhibitors [MoA]In Bloodaspects of radiation effectschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Inhibiting adenosine deaminase modulates the systemic inflammatory response syndrome in endotoxemia and sepsis.
By pharmacological manipulation of endogenous adenosine, using chemically distinct methods, we tested the hypothesis that… 
Highly Cited
1995
Highly Cited
1995
Adenosine‐induced apoptosis in chick embryonic sympathetic neurons: a new physiological role for adenosine.
1. A newly found action of adenosine in neurons, which may have an important physiological function in the growth and development… 
1994
1994
Endothelial nucleotide catabolism and adenosine production.
OBJECTIVE The aim was to study pathways of nucleotide catabolism and adenosine production in cultured human umbilical vein… 
1985
1985
Adechlorin, a new adenosine deaminase inhibitor containing chlorine production, isolation and properties.
Adechlorin exhibiting a potent inhibitory activity against calf intestinal adenosine deaminase was isolated from the cultured… 
1984
1984
Adenosine inhibits cell division and promotes neurite extension in PC12 cells
Low concentrations (10–50 μM) of adenosine (EC50 = 17 μM) or chloroadenosine (EC50 = 23 μM) prevent the division of PC12 cells… 
Highly Cited
1983
Highly Cited
1983
Selective overproduction of adenosine deaminase in cultured mouse cells.
The objective of this work was to isolate cultured mouse cells with amplified adenosine deaminase genes. Such cell lines should… 
1982
1982
Purine metabolism in relation to leukemia and lymphoid cell differentiation.
Highly Cited
1981
Highly Cited
1981
Role of adenosine in adipose tissue circulation.
The vasodilatory effect of adenosine and some related compounds were studied in subcutaneous adipose tissue in situ. The effects… 
Highly Cited
1979
Highly Cited
1979
Adenine nucleotide degradation during energy depletion in human lymphoblasts. Adenosine accumulation and adenylate energy charge correlation.
Adenine nucleotide breakdown to nucleosides and purine bases was measured in cultures of human lymphoblastoid cells following: 1… 
1976
1976
Antiviral Activity of Arabinosyladenine and Arabinosylhypoxanthine in Herpes Simplex Virus-Infected KB Cells: Selective Inhibition of Viral Deoxyribonucleic Acid Synthesis in the Presence of an…
The antiviral activity of the fraudulent nucleoside arabinosyladenine (ara-A) against herpes simplex virus (HSV) type 1 was… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)