Adenosine Deaminase Inhibitors

Known as: ADA Inhibitors, ADA Inhibitor, Inhibitors, Adenosine Deaminase 
Any substance that inhibits adenosine deaminase, an enzyme involved with the degradation of adenine in purine metabolism and that acts as a positive… (More)
National Institutes of Health

Papers overview

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2007
2007
Adenosine modulates the immune system and inhibits inflammation via reduction of cytokine biosynthesis and neutrophil functions… (More)
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2006
2006
The interactions between four inhibitors and adenosine deaminase (ADA) were examined by calculating their binding free energies… (More)
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2006
2006
Adenosine has anti-inflammatory activity. Adenosine deaminase (EC 3.5.4.4) metabolizes extracellular adenosine, resulting in an… (More)
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1998
1998
The present study examined the spinal antinociceptive effects of adenosine analogs and inhibitors of adenosine kinase and… (More)
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1998
1998
The objective of this study was to characterize the effects of exogenous and endogenous (cardiac fibroblast-derived) adenosine on… (More)
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Highly Cited
1997
Highly Cited
1997
The purine nucleoside adenosine (9-beta-D-ribofuranosyladenine) inhibits a number of lymphocyte functions in vitro, including the… (More)
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1997
1997
The physiological role of adenosine (Ado) is well known. Although a number of pharmacological attempts have been made to… (More)
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1997
1997
Puromycin aminonucleoside (PAN) toxicity was totally inhibited in the rat in vivo and in cultured glomerular epithelial cells… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Because proliferation of cardiac fibroblasts participates in cardiac hypertrophy/remodeling associated with… (More)
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1996
1996
Inhibitors of adenosine kinase, but not adenosine deaminase, produce antinociception when administered spinally. In this study… (More)
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