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Adenosine Deaminase Inhibitors

Known as: ADA Inhibitors, ADA Inhibitor, Inhibitors, Adenosine Deaminase 
Any substance that inhibits adenosine deaminase, an enzyme involved with the degradation of adenine in purine metabolism and that acts as a positive… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Extracellular adenosine-induced apoptosis of CW2 human colonic cancer cells by activating caspase-3, -8 and -9, and the effect… Expand
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Highly Cited
2007
Highly Cited
2007
Adenosine modulates the immune system and inhibits inflammation via reduction of cytokine biosynthesis and neutrophil functions… Expand
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Review
1999
Review
1999
T HIS STORY BEGINS with a seminal case report describing a 16-year-old boy who presented with acute lymphoblastic leukemia (ALL… Expand
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Highly Cited
1998
Highly Cited
1998
&NA; The present study examined the spinal antinociceptive effects of adenosine analogs and inhibitors of adenosine kinase and… Expand
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Highly Cited
1997
Highly Cited
1997
The purine nucleoside adenosine (9-beta-D-ribofuranosyladenine) inhibits a number of lymphocyte functions in vitro, including the… Expand
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Highly Cited
1991
Highly Cited
1991
Abstract: The effects of a potent adenosine deaminase inhibitor, deoxycoformycin, on purine and amino acid neuro‐transmitter… Expand
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Highly Cited
1984
Highly Cited
1984
Selective failure of lymphoid development occurs in genetic deficiency of adenosine deaminase (ADA). We examined the in vivo… Expand
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Highly Cited
1982
Highly Cited
1982
A thin dialysis tube was implanted stereotaxically under halothane anesthesia in the caudate nucleus of Sprague-Dawley rats and… Expand
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Highly Cited
1977
Highly Cited
1977
Abstract The specificity of the potent adenosine deaminase inhibitors deoxycoformycin (covidarabine), coformycin and erythro -9… Expand
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Highly Cited
1976
Highly Cited
1976
The biochemical mechanisms by which a genetically determined deficiency of adenosine deaminase leads to immunodeficiency are… Expand
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