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Adenosine Deaminase Inhibitors

Known as: ADA Inhibitors, ADA Inhibitor, Inhibitors, Adenosine Deaminase 
Any substance that inhibits adenosine deaminase, an enzyme involved with the degradation of adenine in purine metabolism and that acts as a positive… 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
By pharmacological manipulation of endogenous adenosine, using chemically distinct methods, we tested the hypothesis that… 
Highly Cited
1995
Highly Cited
1995
1. A newly found action of adenosine in neurons, which may have an important physiological function in the growth and development… 
1994
1994
OBJECTIVE The aim was to study pathways of nucleotide catabolism and adenosine production in cultured human umbilical vein… 
1985
1985
Adechlorin exhibiting a potent inhibitory activity against calf intestinal adenosine deaminase was isolated from the cultured… 
1984
1984
Low concentrations (10–50 μM) of adenosine (EC50 = 17 μM) or chloroadenosine (EC50 = 23 μM) prevent the division of PC12 cells… 
Highly Cited
1983
Highly Cited
1983
The objective of this work was to isolate cultured mouse cells with amplified adenosine deaminase genes. Such cell lines should… 
Highly Cited
1981
Highly Cited
1981
The vasodilatory effect of adenosine and some related compounds were studied in subcutaneous adipose tissue in situ. The effects… 
Highly Cited
1979
Highly Cited
1979
Adenine nucleotide breakdown to nucleosides and purine bases was measured in cultures of human lymphoblastoid cells following: 1…