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Formycins

Known as: Formycins [Chemical/Ingredient], formycin 
Pyrazolopyrimidine ribonucleosides isolated from Nocardia interforma. They are antineoplastic antibiotics with cytostatic properties.
National Institutes of Health

Related topics

Related topics

28 relations

Narrower (19)

2'-deoxyformycin A2-aminoformycin2-fluoroformycin2-methylformycin

Broader (3)

Antibiotics, AntineoplasticNucleoside Analogspyrazolopyrimidine
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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Highly Cited
1994
Highly Cited
1994
X-ray structure of recombinant ricin A-chain at 1.8 A resolution.
Ricin is a potent plant toxin which acts by removing a specific adenine residue from the ribosome. The X-ray crystal structure of… 
1990
1990
Preparation of modified nucleosides from glucosamine: rapid and efficient formal total synthesis of several 2′-deoxy C-nucleosides
Formal total syntheses of several 2′-deoxy C-nucleosides have been accomplished in a short and efficient process using D… 
1984
1984
The effect of formycin B on mRNA translation and uptake of purine precursors in Leishmania mexicana.
Formycin B is a structural analog of inosine that is a potent inhibitor of Leishmania multiplication. Formycin B is reportedly… 
Highly Cited
1974
Highly Cited
1974
Structural studies on phenylalanine transfer ribonucleic acid from yeast with the spectroscopic label formycin.
Formycinmonophosphate (FMP) has been incorporated in to the 3′-terminus of phenylalanine tRNA from yeast by tRNA nucleotidyl… 
Highly Cited
1972
Highly Cited
1972
Interference with nucleoside transport in mouse lymphoma cells proliferating in culture.
Summary The S-nitrobenzyl derivatives of 6-thio-9-β-d-ribofuranosylpurine and 2-amino-6-thio-9-β-d-ribofuranosylpurine (i.e… 
Highly Cited
1971
Highly Cited
1971
Nucleoside transport. I. A mediated process in human erythrocytes.
The transport of nucleosides by human erythrocytes has been studied by measuring disappearance of 14C-labelled uridine and… 
1969
1969
The metabolism of formycin, an adenosine analogue.
Formycin, a C-glycoside analogue of adenosine, is rapidly converted to phosphorylated derivatives by Ehrlich ascites tumor cells… 
1968
1968
Metabolism of formycin and formycin B in vitro.
Formycin and formycin B are excreted into urine in their metabolized form which was isolated. This metabolized product was found… 
1968
1968
Biochemical effects of formycin B on Xanthomonas oryzae.
Formycin B, an inosine analogue, inhibits the incorporation of radioactive adenosine, uridine and thymidine, but none of formic… 
1967
1967
Resistance to purine ribonucleoside analogues in an ascites tumor.
A tumor subline (EAC-R2) which is resistant to the growth-inhibitory effects of 6-(methylmercapto)purine ribonucleoside (Me6MPR…