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Formycins
Known as:
Formycins [Chemical/Ingredient]
, formycin
Pyrazolopyrimidine ribonucleosides isolated from Nocardia interforma. They are antineoplastic antibiotics with cytostatic properties.
National Institutes of Health
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Related topics
Related topics
28 relations
Narrower (19)
2'-deoxyformycin A
2-aminoformycin
2-fluoroformycin
2-methylformycin
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Broader (3)
Antibiotics, Antineoplastic
Nucleoside Analogs
pyrazolopyrimidine
In Blood
agonists
antagonists & inhibitors
aspects of radiation effects
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1990
1990
Preparation of modified nucleosides from glucosamine: rapid and efficient formal total synthesis of several 2′-deoxy C-nucleosides
M. E. Jung
,
Ivan D. Trifunovich
,
J. Gardiner
,
Gary L. Clevenger
1990
Corpus ID: 85399149
Formal total syntheses of several 2′-deoxy C-nucleosides have been accomplished in a short and efficient process using D…
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1985
1985
Antileishmanial activity of human red blood cells containing formycin A.
J. Berman
,
J. V. Gallalee
Journal of Infectious Diseases
1985
Corpus ID: 40427865
Formycin B is the most active antileishmanial agent in vitro because it is metabolized by the parasites to formycin A phosphates…
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1984
1984
The effect of formycin B on mRNA translation and uptake of purine precursors in Leishmania mexicana.
L. Nolan
,
J. Berman
,
L. Giri
Biochemistry International
1984
Corpus ID: 29735165
Formycin B is a structural analog of inosine that is a potent inhibitor of Leishmania multiplication. Formycin B is reportedly…
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1978
1978
Metabolism of tubercidin and formycin to their 3':5'-cyclic nucleotides in mammalian cells.
T. Zimmerman
,
G. Wolberg
,
G. S. Duncan
Journal of Biological Chemistry
1978
Corpus ID: 3206049
High performance anion exchange chromatography was utilized to demonstrate extensive metabolism of tubercidin and formycin to…
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1975
1975
Cyclonucleoside derivatives of formycin.
Osamu Makabe
,
Masakazu Nakamura
,
S. Umezawa
Journal of antibiotics (Tokyo. )
1975
Corpus ID: 973896
Sir: Formycin1) is a representative pyrazolopyri-midine nucleoside that contains the unusual C-riboside linkage and its…
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1975
1975
Phenylalanyl-tRNA synthetase from baker's yeast: role of 3'-terminal adenosine of tRNA-Phe in enzyme-substrate interaction studied with 3'-modified tRNA-Phe species.
F. Von der Haar
,
E. Gaertner
Proceedings of the National Academy of Sciences…
1975
Corpus ID: 22493924
TRNA-Phe species from baker's yeast modified at the 3'-terminus in many cases are phenylalanylatable substrates. Out of several…
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1969
1969
The metabolism of formycin, an adenosine analogue.
I. C. Caldwell
,
J. Henderson
,
Alan R. P. Paterson
Canadian Journal of Biochemistry
1969
Corpus ID: 39990647
Formycin, a C-glycoside analogue of adenosine, is rapidly converted to phosphorylated derivatives by Ehrlich ascites tumor cells…
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1969
1969
Effects of several tumor-inhibitory antibiotics on immunological responses.
Hiroshi Yamaki
,
Nobuo Tanaka
,
Hamao Umezawa
Journal of antibiotics (Tokyo. )
1969
Corpus ID: 1881687
The effects of various tumor-inhibitory antibiotics on immunological responses were investigated, using serum antibody production…
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1968
1968
Biochemical effects of formycin B on Xanthomonas oryzae.
M. Hori
,
T. Wakashiro
,
Etsuko Ito
,
T. Sawa
,
T. Takeuchi
,
Hamao Umezawa
Journal of antibiotics (Tokyo. )
1968
Corpus ID: 26340590
Formycin B, an inosine analogue, inhibits the incorporation of radioactive adenosine, uridine and thymidine, but none of formic…
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1968
1968
Metabolism of formycin and formycin B in vitro.
Masaaki Ishizuka
,
T. Sawa
,
G. Koyama
,
T. Takeuchi
,
Hamao Umezawa
Journal of antibiotics (Tokyo. )
1968
Corpus ID: 26338201
Formycin and formycin B are excreted into urine in their metabolized form which was isolated. This metabolized product was found…
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