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N-n-propylnorapomorphine

Known as: N-propylnorapomorphine, n-propylapomorphine, 6-propylnorapomorphine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2014
02419732014

Related topics

Related topics

4 relations

Broader (3)

Antiparkinson AgentsApomorphineDopamine Agonists
analogs & derivatives

Related mentions per year

Related mentions per year

1945-2018
19401960198020002020
N-n-propylnorapomorphine
Apomorphine
Dopamine Agonists
Antiparkinson Agents
analogs & derivatives

Papers overview

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2009
2009
Quantitative PET analysis of the dopamine D2 receptor agonist radioligand 11C-(R)-2-CH3O-N-n-propylnorapomorphine in the human brain.
UNLABELLED It has been demonstrated in vitro that the dopamine D(2) receptor has 2 interconvertible affinity states for… (More)
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2007
2007
Amphetamine-induced dopamine release: duration of action as assessed with the D2/3 receptor agonist radiotracer (-)-N-[(11)C]propyl-norapomorphine ([11C]NPA) in an anesthetized nonhuman primate.
 
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Highly Cited
2006
Highly Cited
2006
Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride.
PET measurements of stimulant-induced dopamine (DA) release are typically performed with antagonist radioligands that bind to… (More)
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Highly Cited
2004
Highly Cited
2004
In vivo vulnerability to competition by endogenous dopamine: comparison of the D2 receptor agonist radiotracer (-)-N-[11C]propyl-norapomorphine ([11C]NPA) with the D2 receptor antagonist radiotracer…
(-)-N-Propyl-norapomorphine (NPA) is a full dopamine (DA) D2 receptor agonist and [11C]NPA is a suitable radiotracer to image D2… (More)
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2003
2003
Kinetics of the uptake and distribution of the dopamine D(2,3) agonist (R)-N-[1-(11)C]n-propylnorapomorphine in brain of healthy and MPTP-treated Göttingen miniature pigs.
The binding of radioligand agonists to dopamine receptors in living brain can be informative about the abundance of receptors… (More)
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1995
1995
Neurotensin peptides antagonistically regulate postsynaptic dopamine D2 receptors in rat nucleus accumbens: a receptor binding and microdialysis study
An in vitro receptor binding and in vivo microdialysis study was performed to further investigate the modulation of dopamine (DA… (More)
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1989
1989
Differences in dopamine receptor reserve for N-n-propylnorapomorphine enantiomers: single unit recording studies after partial inactivation of receptors by N-ethoxycarbonyl-2-ethoxy-1,2…
Previous studies with (S)-(+)-N-n-propylnorapomorphine (NPA), an enantiomer of the potent dopaminergic agonist (R)-(-)-NPA… (More)
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1986
1986
Regional in vivo binding of the substituted benzamide [3H]eticlopride in the rat brain: evidence for selective labelling of dopamine receptors.
The novel substituted benzamide eticlopride, (S)-(-)-5-chloro-3-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-methoxy salicylamide… (More)
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1985
1985
Mesolimbic dopamine function is not altered during continuous chronic treatment of rats with typical or atypical neuroleptic drugs
Rats were treated continuously for up to 20 months with either haloperidol (1.4–1.6 mg/kg/day), sulpiride (102–109 mg/kg/day) or… (More)
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1976
1976
Dopamine-like renal and mesenteric vasodilation caused by apomorphine 6-propylnorapomorphine and 2-amino-6, 7-dihydroxy-l,2,3,4-tetrahydronaphthalene
DOPAMINE has several unique actions in the central nervous system (CNS)—particularly the striatum—and in blood vessels, which… (More)
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