Skip to search formSkip to main contentSkip to account menu

Apomorphine

Known as: (R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, Apomorphin, Apomorphine [Chemical/Ingredient] 
A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also… 
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (17)

10,11-dihydroxy-N-methylnorapomorphine10,11-methylenedioxy-N-propylnoraporphine2-fluoro-N-n-propylnorapomorphineApokyn

Broader (9)

AlkaloidsAntiparkinson AgentsAporphinesDopamine Agonists
Apomorphine DiacetateIn BloodUprimaagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1996
Highly Cited
1996
Nicotinic, muscarinic and dopaminergic actions in the ventral hippocampus and the nucleus accumbens: effects on spatial working memory in rats
Highly Cited
1988
Highly Cited
1988
Transient behavioral recovery in hemiparkinsonian primates after adrenal medullary allografts.
Highly Cited
1987
Highly Cited
1987
Effects of D1 and D2 dopamine receptor stimulation on the activity of substantia nigra pars reticulata neurons in 6-hydroxydopamine lesioned rats: D1/D2 coactivation induces potentiated responses
Highly Cited
1985
Highly Cited
1985
Selective D2 dopamine receptor agonists prevent catalepsy induced by SCH 23390, a selective D1 antagonist.
Highly Cited
1984
Highly Cited
1984
Repeated administration of N-methyl-4-phenyl 1,2,5,6-tetrahydropyridine to rats is not toxic to striatal dopamine neurones.
Highly Cited
1983
Highly Cited
1983
Effect of injections of 6-OHDA into either nucleus accumbens septi or frontal cortex on spontaneous and drug-induced activity
Highly Cited
1981
Highly Cited
1981
3-PPP, a new centrally acting DA-receptor agonist with selectivity for autoreceptors.
Highly Cited
1979
Highly Cited
1979
Presynaptic subsensitivity as a possible basis for sensitization by long-term dopamine mimetics.
Highly Cited
1979
Highly Cited
1979
Interactions between serotonergic and dopaminergic systems in rat brain demonstrated by small unilateral lesions of the raphe nuclei.
Highly Cited
1973
Highly Cited
1973
Morphine-induced muscular rigidity in rats.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)