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Apomorphine

Known as: (R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, Apomorphin, Apomorphine [Chemical/Ingredient] 
A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also… 
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (17)

10,11-dihydroxy-N-methylnorapomorphine10,11-methylenedioxy-N-propylnoraporphine2-fluoro-N-n-propylnorapomorphineApokyn

Broader (9)

AlkaloidsAntiparkinson AgentsAporphinesDopamine Agonists
Apomorphine DiacetateIn BloodUprimaagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1988
Highly Cited
1988
Transient behavioral recovery in hemiparkinsonian primates after adrenal medullary allografts.
Highly Cited
1987
Highly Cited
1987
Effects of D1 and D2 dopamine receptor stimulation on the activity of substantia nigra pars reticulata neurons in 6-hydroxydopamine lesioned rats: D1/D2 coactivation induces potentiated responses
Highly Cited
1984
Highly Cited
1984
The yawning-penile erection syndrome as a model for putative dopamine autoreceptor activity.
Highly Cited
1982
Highly Cited
1982
Plasticity of neostriatal dopamine receptors after nigrostriatal injury: Relationship to recovery of sensorimotor functions and behavioral supersensitivity
Highly Cited
1981
Highly Cited
1981
3-PPP, a new centrally acting DA-receptor agonist with selectivity for autoreceptors.
Highly Cited
1979
Highly Cited
1979
Involvement of catecholamines in kindled amygdaloid convulsions in the rat
Highly Cited
1979
Highly Cited
1979
Presynaptic subsensitivity as a possible basis for sensitization by long-term dopamine mimetics.
Highly Cited
1978
Highly Cited
1978
The striatal dopaminergic function is mediated by the inhibition of a nigral, non-dopaminergic neuronal system via a strio-nigral GABAergic pathway.
Highly Cited
1975
Highly Cited
1975
Effects of dopaminergic receptor agonists and antagonists on the activity of the neo-striatal cholinergic system
Highly Cited
1973
Highly Cited
1973
Morphine-induced muscular rigidity in rats.
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