G. C. Cotzias

Publications172
h-index42
Citations8,558
Highly Influential Citations109
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Aromatic amino acids and modification of parkinsonism.
TLDR
The interrelations between melanogenesis and extrapyramidal disease might be of fundamental importance and it was noted that chronic Parkinson's disease has a common precursor in the synthesis of both melanin and catecholamines. Expand
Modification of Parkinsonism--chronic treatment with L-dopa.
Chronic manganese poisoning
TLDR
Arguments in favor of the thesis that chronic manganese poisoning may diverge significantly from the aforementioned diseases are developed. Expand
Modification of Parkinsonism--chronic treatment with L-dopa.
Abstract Slowly increasing oral doses of L-3,4-dihydroxyphenylalanine (L-dopa) induced at least partial improvement of some manifestations in a series of 28 patients with Parkinsonism. Improvement of… Expand
Manganese in health and disease.
TLDR
The manganese in health and disease is one book that the authors really recommend you to read, to get more solutions in solving this problem. Expand
Metabolic modification of Parkinson's disease and of chronic manganese poisoning.
Chronic manganese poisoning Clearance of tissue manganese concentrations with persistence of the neurological picture
TLDR
This study investigated whether the rapidly excreted metal was located in a single major pool or in a system if interconnecting pools, and found that healthy, working miners had accelerated tissue turnovers of radiomanganese in contrast to the poisoned ex-miners who had normal turnovers. Expand
Chronic manganese poisoning
TLDR
A fitting inquiry was made into metabolic determinants which might render susceptible some of the exposed workers susceptible to manganism, which argues that the bulk of the inhaled manganese becomes transferred into the gastrointestinal tract, from which it is either absorbed or eliminated. Expand
Treatment of Parkinson's disease with aporphines. Possible role of growth hormone.
TLDR
N-propylnoraporphine is very useful in the treatment of Parkinson's disease and seems to abolish tachyphylaxis, in patients previously on prolonged levodopa administration. Expand
Levodopa, fertility, and longevity.
High concentrations of the dopaminergic drug levodopa (L-dopa, L-3,4-dihydroxphenylalanine) administered to mice in their diet affected fertility to a moderate degree and prolonged the mean life-span… Expand
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