Aromatic amino acids and modification of parkinsonism.
- G. C. Cotzias, M. V. Van Woert, L. Schiffer
- BiologyNew England Journal of Medicine
- 16 February 1967
The interrelations between melanogenesis and extrapyramidal disease might be of fundamental importance and it was noted that chronic Parkinson's disease has a common precursor in the synthesis of both melanin and catecholamines.
Modification of Parkinsonism--chronic treatment with L-dopa.
- G. C. Cotzias, P. Papavasiliou, R. Gellene
- MedicineNew England Journal of Medicine
- 13 February 1969
Abstract Slowly increasing oral doses of L-3,4-dihydroxyphenylalanine (L-dopa) induced at least partial improvement of some manifestations in a series of 28 patients with Parkinsonism. Improvement of…
Chronic manganese poisoning
- I. Mena, O. Marin, S. Fuenzalida, G. C. Cotzias
- MedicineNeurology
- 1 February 1967
Arguments in favor of the thesis that chronic manganese poisoning may diverge significantly from the aforementioned diseases are developed.
Manganese in health and disease.
- G. C. Cotzias
- MedicinePhysiological Reviews
- 1 July 1958
The manganese in health and disease is one book that the authors really recommend you to read, to get more solutions in solving this problem.
Metabolic modification of Parkinson's disease and of chronic manganese poisoning.
- G. C. Cotzias, P. Papavasiliou, J. Ginos, A. Steck, S. Düby
- MedicineAnnual Review of Medicine
- 1971
Chronic manganese poisoning Clearance of tissue manganese concentrations with persistence of the neurological picture
- G. C. Cotzias, Kazuke Horiuchi, S. Fuenzalida, Ismael Mena
- MedicineNeurology
- 1 April 1968
This study investigated whether the rapidly excreted metal was located in a single major pool or in a system if interconnecting pools, and found that healthy, working miners had accelerated tissue turnovers of radiomanganese in contrast to the poisoned ex-miners who had normal turnovers.
Interdependence of routes excreting manganese.
- A. Bertinchamps, S. Miller, G. C. Cotzias
- Biology, MedicineAmerican Journal of Physiology
- 1 July 1966
Treatment of Parkinson's disease with aporphines. Possible role of growth hormone.
- G. C. Cotzias, P. Papavasiliou, E. Tolosa, J. Mendez, M. Bell-Midura
- Medicine, BiologyNew England Journal of Medicine
- 11 March 1976
N-propylnoraporphine is very useful in the treatment of Parkinson's disease and seems to abolish tachyphylaxis, in patients previously on prolonged levodopa administration.
Injected apomorphine and orally administered levodopa in Parkinsonism.
- S. Düby, G. C. Cotzias, P. Papavasiliou, W. H. Lawrence
- Psychology, BiologyArchives of Neurology
- 1 December 1972
The dichotomy between synergistic and antagonistic effects may be explained by the molecule of apomorphine, part of which resembles dopamine and the other resembles phenylethylamine, which can displace neurotransmitters from cellular sites.
Chronic manganese poisoning
- I. Mena, Kazuko Horiuchi, Kathleen E. Burke, G. C. Cotzias
- MedicineNeurology
- 1 October 1969
A fitting inquiry was made into metabolic determinants which might render susceptible some of the exposed workers susceptible to manganism, which argues that the bulk of the inhaled manganese becomes transferred into the gastrointestinal tract, from which it is either absorbed or eliminated.
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