Skip to search formSkip to main contentSkip to account menu

Mechlorethamine

Known as: N-Methyl-bis(beta-chloroethyl)amine, Nitrogen Mustard, Methylchlorethamine 
A synthetic agent related to sulphur mustard with antineoplastic and immunosuppressive properties. Nitrogen mustard (a member of a family of… 
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (19)

4-(methylsulfinyl)phenyl nitrogen mustardCaryolysineCloraminEmbichin
Alkylating Activity [MoA]Communicable DiseasesDrug AllergyHodgkin Disease

Broader (9)

Alkylating AgentsAminesAntineoplastic AgentsAntineoplastic Agents, Alkylating

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Exfoliated PP/Clay Nanocomposites Using Ammonium-Terminated PP as the Organic Modification for Montmorillonite
Although the miscibility of silicates, including clay minerals, with organics and polymers has been known since the early 1950s… 
Highly Cited
1996
Highly Cited
1996
Toward antibody-directed "abzyme" prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing.
Antibody-directed enzyme prodrug therapy, ADEPT, is a recent approach to targeted cancer chemotherapy intended to diminish the… 
Highly Cited
1989
Highly Cited
1989
Generation of elusive neutrals and dications by neutralization resp. Charge stripping of monocations in beam experiments
Abstract 
Highly Cited
1983
Highly Cited
1983
Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues.
Platelet-activating factor (1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine; PAF) induces a specific, dose-dependent contraction… 
Highly Cited
1979
Highly Cited
1979
Conformation of gramicidin A channel in phospholipid vesicles: a 13C and 19F nuclear magnetic resonance study.
We have determined the conformation of the channel-forming polypeptide antibiotic gramicidin A in phosphatidylcholine vesicles by… 
Highly Cited
1979
Highly Cited
1979
Comparison of the substrate specificity of adenosine 3':5'-monophosphate- and guanosine 3':5'-monophosphate-dependent protein kinases. Kinetic studies using synthetic peptides corresponding to…
The substrate specificities of cyclic GMP-dependent and cyclic AMP-dependent protein kinases have been compared by kinetic… 
Highly Cited
1979
Highly Cited
1979
Characterization of "thyroliberin-deamidating enzyme" as a post-proline-cleaving enzyme. Partial purification and enzyme-chemical analysis of the enzyme from anterior pituitary tissue.
An enzyme which catalyzes the deamidation of thyroliberin (TRF; less than Glu-His-Pro-NH2) has been purified 110-fold from… 
Highly Cited
1970
Highly Cited
1970
Porcine thyrotropin releasing hormone is (pyro)glu-his-pro(NH2).
Porcine thyrotropin releasing hormone, isolated from the hypothalamus, and synthetic L-(pyro)Glu-L-His-L-Pro(NH2) are… 
Highly Cited
1954
Highly Cited
1954
Derivation of stable polyploid sublines from a hyperdiploid Ehrlich ascites carcinoma.
Summary Repeatable experimental production of polyploid sublines from the hyper-diploid Ehrlich ascites carcinoma has been… 
Highly Cited
1954
Highly Cited
1954
Studies on pathogenesis of amyloidosis. II. Effect of nitrogen mustard in inducing amyloidosis.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)