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Mechlorethamine

Known as: N-Methyl-bis(beta-chloroethyl)amine, Nitrogen Mustard, Methylchlorethamine 
A synthetic agent related to sulphur mustard with antineoplastic and immunosuppressive properties. Nitrogen mustard (a member of a family of… 
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (19)

4-(methylsulfinyl)phenyl nitrogen mustardCaryolysineCloraminEmbichin
Alkylating Activity [MoA]Communicable DiseasesDrug AllergyHodgkin Disease

Broader (9)

Alkylating AgentsAminesAntineoplastic AgentsAntineoplastic Agents, Alkylating

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1995
Highly Cited
1995
X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.
Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases involved in tissue remodeling. They have also been… 
Highly Cited
1991
Highly Cited
1991
Nitric oxide synthesis in the CNS endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues.
Highly Cited
1991
Highly Cited
1991
Novel purification of the catalytic domain of Golgi alpha-mannosidase II. Characterization and comparison with the intact enzyme.
Highly Cited
1984
Highly Cited
1984
Prothymosin alpha: isolation and properties of the major immunoreactive form of thymosin alpha 1 in rat thymus.
A polypeptide containing approximately equal to 112 amino acid residues, with the thymosin alpha 1 sequence at its NH2 terminus… 
Highly Cited
1983
Highly Cited
1983
Amino acid sequence of the catalytic subunit of bovine type II adenosine cyclic 3',5'-phosphate dependent protein kinase.
The 350-residue amino acid sequence of the catalytic subunit of bovine cardiac muscle adenosine cyclic 3',5'-phosphate dependent… 
Highly Cited
1979
Highly Cited
1979
Purification and distribution of a major protein in rat prostate that binds estramustine, a nitrogen mustard derivative of estradiol-17 beta.
A protein in rat ventral prostate cytosol that binds estramustine [estradiol 3-bis(2-chloroethyl)carbamate) was purified to… 
Highly Cited
1976
Highly Cited
1976
Characterization of postreplication repair in mutagen-sensitive strains of Drosophila melanogaster.
Mutants of Drosophila melanogaster, with suspected repair deficiencies, were analyzed for their capacity to repair damage induced… 
Highly Cited
1973
Highly Cited
1973
Carboxypeptidase from yeast. Large scale preparation and the application to COOH-terminal analysis of peptides and proteins.
Abstract In order to render the carboxypeptidase from yeast more readily available for use in sequence studies in protein… 
Highly Cited
1972
Highly Cited
1972
Horse liver aldehyde dehydrogenase. I. Purification and characterization.
Review
1968
Review
1968
The photochemistry, photobiology, and repair of polynucleotides.
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