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Mechlorethamine

Known as: N-Methyl-bis(beta-chloroethyl)amine, Nitrogen Mustard, Methylchlorethamine 
A synthetic agent related to sulphur mustard with antineoplastic and immunosuppressive properties. Nitrogen mustard (a member of a family of… 
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (19)

4-(methylsulfinyl)phenyl nitrogen mustardCaryolysineCloraminEmbichin
Alkylating Activity [MoA]Communicable DiseasesDrug AllergyHodgkin Disease

Broader (9)

Alkylating AgentsAminesAntineoplastic AgentsAntineoplastic Agents, Alkylating

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry.
Highly Cited
1998
Highly Cited
1998
Chemical modification of titanium surfaces for covalent attachment of biological molecules.
The surface of implantable biomaterials is in direct contact with the host tissue and plays a critical role in determining… 
Highly Cited
1996
Highly Cited
1996
The Mammalian Immediate-early TIS21 Protein and the Leukemia-associated BTG1 Protein Interact with a Protein-arginine N-Methyltransferase*
The TIS21 immediate-early gene and leukemia-associated BTG1 gene encode proteins with similar sequences. Two-hybrid analysis… 
Highly Cited
1993
Highly Cited
1993
Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.
Highly Cited
1993
Highly Cited
1993
NG-nitro L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists.
Analogues of L-arginine with modifications at the terminal guanidino nitrogen and/or the carboxyl terminus of the molecule have… 
Highly Cited
1992
Highly Cited
1992
Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties.
Highly Cited
1992
Highly Cited
1992
The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain.
Synovial fluid was collected from patients with recent knee injury and from patients with early or late stage osteoarthritis… 
Highly Cited
1986
Highly Cited
1986
The murine transforming growth factor-beta precursor.
Highly Cited
1983
Highly Cited
1983
Neuropeptide Y distribution in human brain
Tatemoto and Mutt recently used the presence of a C-terminal NH2 group to identify and isolate a new peptide, neuropeptide Y (NPY… 
Highly Cited
1971
Highly Cited
1971
Glial cell function: uptake of transmitter substances.
Rabbit-brain fractions enriched in neuronal cell bodies and in glial cells accumulated norepinephrine, serotonin, dopamine, and… 
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