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Alkylating Activity [MoA]

Known as: Alkylating Activity 
National Institutes of Health

Papers overview

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2004
2004
SummaryThe disposition of cyclophosphamide and its alkylating metabolites was investigated in a group of myeloma patients with… 
2004
2004
SummaryThe pharmacokinetics of alkylating activity were studied in 17 children treated i.v. with ifosfamide (IF) at 3 g/m2 as a 1… 
1989
1989
In order to develop cytotoxic estrogens with a specific effect on hormone‐dependent mammary tumors, two 1,1,2‐triphenylbut‐1‐enes… 
1986
1986
Several 1,2-bis(arylsulfonyl)-1-methylhydrazines were synthesized and evaluated for antineoplastic activity against the L1210… 
1982
1982
Ten patients with brain tumors and indwelling ventricular reservoirs were pretreated with 5% to 10% dimethyl sulfoxide (DMSO… 
Highly Cited
1981
Highly Cited
1981
Mitomycin C and hyperthermia are both toxic to chronically hypoxic EMT6 tumor cells. Combinations of this drug and heat were… 
Highly Cited
1979
Highly Cited
1979
Abstract 1 Plasma cyclophosphamide levels were estimated by gas-chromatography in seven patients following intravenous and oral… 
Highly Cited
1971
Highly Cited
1971
The authors studied the alkylating activity in the blood serum of man and rats after administration of cyclophosphamide, and its…