Alkylating Activity [MoA]

Known as: Alkylating Activity 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1961-1999
0119611999

Papers overview

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2000
2000
Hydroxymethylacylfulvene (HMAF) is a novel agent with alkylating activity and is a potent inducer of apoptosis that is currently… (More)
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1999
1999
Several substances used in rubber processing are known to be genotoxic. Workers in a rubber tyre factory, exposed to a broad… (More)
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1986
1986
A total of 14 patients, 7 male and 7 female, received in all 21 evaluable courses of cyclophosphamide administered by 5-day… (More)
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1984
1984
Lycurim [1,4-di(2'-methanesulfonyloxyethylamino)-1,4-dideoxymesoerythri tol dimethane sulfonate] is rapidly hydrolyzed in aqueous… (More)
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1983
1983
Alkylating activity of cytostatic drugs was studied in relation to their mutagenicity and toxicity in E. coli WP2 uvrA. Four… (More)
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1982
1982
Ten patients with brain tumors and indwelling ventricular reservoirs were pretreated with 5% to 10% dimethyl sulfoxide (DMSO… (More)
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1981
1981
Mitomycin C and hyperthermia are both toxic to chronically hypoxic EMT6 tumor cells. Combinations of this drug and heat were… (More)
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Highly Cited
1961
Highly Cited
1961
Single doses of cyclophosphamide can regularly induce bladder damage in rats and dogs. Changes develop rapidly and, within ~4… (More)
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