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Altretamine

Known as: Altrétamine, Altretaminum, 1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N'',N''-hexamethyl- 
A synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the… 
National Institutes of Health

Related topics

Related topics

34 relations

Narrower (6)

2,4,6-trimethylmelamineHFAP protocolHexastatHexinawas
Alkylating Activity [MoA]Altretamine 50 MG Oral Capsule [Hexalen]Altretamine/cisplatin/cyclophosphamide/doxorubicin protocolHAC protocol

Broader (1)

Antineoplastic Agents, Alkylating

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Development of an enzyme-linked immunosorbent assay for atrazine mercapturic acid in human urine.
Improved assessments of human exposure to electrophilic chemicals require rapid and inexpensive analytical techniques that can… 
Highly Cited
1989
Highly Cited
1989
Extraction and isolation of triazine herbicides from water and vegetables by a double trap tandem system.
The ability of a two-trap tandem system, one containing a nonspecific adsorbing material, such as graphitized carbon black… 
Highly Cited
1983
Highly Cited
1983
Genetic, biochemical, and cross-resistance studies with mutants of Chinese hamster ovary cells resistant to the anticancer drugs, VM-26 and VP16-213.
The effects of the anticancer drugs 4′-demethylepipodophyllotoxin thenylidene β-d-glucoside and 4′-demethylepipodophyllotoxin… 
Highly Cited
1982
Highly Cited
1982
Toxicity and anticancer activity of a new triazine antifolate (NSC 127755).
A new triazine folate antagonist, 3-chloro-4-((4-(2-chloro-4-[4,6-diamino-2,2-dimethyl-s-triazin-1(2H)-yl]phenyl)butyl… 
Highly Cited
1980
Highly Cited
1980
The binding of heavy meromyosin to F-actin.
The binding of heavy meromyosin (HMM), a soluble two-headed fragment of myosin, to F-actin was examined at mu = 0.22 M, 22… 
1979
1979
Antiphytoviral activity of 2,4 dioxo hexahydro triazine.
Three treatments with 2,4 dioxo hexahydro triazine (DHT) significantly reduced the concentration of potato virus X (PVX) in… 
1979
1979
Disposition and metabolism of pentamethylmelamine and hexamethylmelamine in rabbits and humans.
The disposition and metabolism of pentamethylmelamine (PMM) and hexamethylmelamine (HMM) were studied in the rabbit, and the… 
Highly Cited
1974
Highly Cited
1974
Metabolism of hexamethylmelamine-ring-14C in rats and man.
The metabolism of hexamethylmelamine (HMM), an antineoplastic drug, was studied in man and rats. After administration of HMM-ring… 
Highly Cited
1973
Highly Cited
1973
N-demethylation of the antineoplastic agent hexamethylmelamine by rats and man.
Summary The metabolism and physiological distribution of hexamethylmelamine (HMM), an effective human anticancer chemotherapeutic… 
Review
1970
Review
1970
Quantitative determination of triazine herbicides in soils by chemical analysis.
Reliable methods for the chemical analysis of soils for the presence of triazine herbicide are of great importance in determining… 
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