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Antineoplastic Agents, Alkylating

Known as: Alkylating Antineoplastic Agents, Alkylating Antineoplastic Drugs, [AN100] ANTINEOPLASTICS,ALKYLATING AGENTS 
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular… 
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Antineoplastic agent-induced pulmonary toxicity is an important cause of respiratory failure. Although the incidence of… 
Highly Cited
2004
Highly Cited
2004
O6-alkylguanine-DNA alkyltransferase (AGT), or O6-methylguanine-DNA methyltransferase (MGMT), prevents mutations and apoptosis… 
Highly Cited
2001
Highly Cited
2001
Sesquiterpene lactones (SLs) have potent anti-inflammatory properties. We have shown previously that they exert this effect in… 
Highly Cited
1997
Highly Cited
1997
  • K. Das, C. White
  • The Journal of biological chemistry
  • 1997
  • Corpus ID: 20101466
Paclitaxel can induce tumor necrosis factor (TNF) and interleukin-1 gene expression, similar to lipopolysaccharides. Since… 
Review
1990
Review
1990
  • A. Pegg
  • Cancer research
  • 1990
  • Corpus ID: 18843385
Alkylating agents and compounds converted metabolically to alkylating agents form an important class of carcinogens and mutagens… 
Highly Cited
1989
Highly Cited
1989
Abstract Study Objective:To assess the activity of taxol in patients with advanced, progressive, and drug-refractory ovarian… 
Highly Cited
1985
Highly Cited
1985
DNA repair-deficient mutants from five genetic complementation groups isolated previously from Chinese hamster cells were assayed… 
Highly Cited
1979
Highly Cited
1979
THE mutagenic lesion O6-methylguanine (O6-MeG) is slowly but actively removed from DNA in Escherichia coli cells treated with…