Antineoplastic Agents, Alkylating

Known as: Alkylating Antineoplastic Agents, Alkylating Antineoplastic Drugs, [AN100] ANTINEOPLASTICS,ALKYLATING AGENTS 
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
PURPOSE Recent studies suggest that temozolomide has activity in neuroendocrine tumors. Low levels of the DNA repair enzyme, O(6… (More)
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Review
2008
Review
2008
Antineoplastic agent-induced pulmonary toxicity is an important cause of respiratory failure. Although the incidence of… (More)
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Highly Cited
2008
Highly Cited
2008
Aluminium (Al) was evaluated for induction of oxidative stress and DNA damage employing the growing roots of Allium cepa L. as… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Various chemotherapy agents, especially of the alkylating category, have been associated with premature ovarian… (More)
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Review
2004
Review
2004
Thioredoxins (Trx) are members of an evolutionarily conserved family of redox-active proteins containing a conserved active site… (More)
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Highly Cited
2004
Highly Cited
2004
O6-alkylguanine-DNA alkyltransferase (AGT), or O6-methylguanine-DNA methyltransferase (MGMT), prevents mutations and apoptosis… (More)
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Highly Cited
2001
Highly Cited
2001
Sesquiterpene lactones (SLs) have potent anti-inflammatory properties. We have shown previously that they exert this effect in… (More)
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Review
1990
Review
1990
Alkylating agents and compounds converted metabolically to alkylating agents form an important class of carcinogens and mutagens… (More)
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Highly Cited
1987
Highly Cited
1987
Seven patients with advanced multiple myeloma, refractory to therapy with alkylating agent-VAD (vincristine-adriamycin… (More)
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Highly Cited
1985
Highly Cited
1985
DNA repair-deficient mutants from five genetic complementation groups isolated previously from Chinese hamster cells were assayed… (More)
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