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Busulfan

Known as: 1,4-Butanediol Dimethylsulfonate, BUS, Sulfabutin 
A synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood… 
National Institutes of Health

Related topics

Related topics

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Narrower (12)

1,4-butanediol diisethionateBusulfan WellcomeBusulfexGT 41
10 ML Busulfan 6 MG/ML Injection [Busulfex]Alkylating Activity [MoA]Busulfan 2 MG Oral Tablet [Myleran]Busulfan:MCnc:Pt:Ser/Plas:Qn

Broader (7)

Alkylating AgentsAntineoplastic AgentsAntineoplastic Agents, AlkylatingImmunosuppressive Agents

Papers overview

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2009
2009
Differences in the proliferative activity of myelocytes from bone marrow, spleen and peripheral blood in chronic myeloid leukaemia.
Cells from bone marrow, spleen and peripheral blood from 8 patients with chronic myeloid leukaemia were incubated with tritiated… 
2004
2004
Imatinib induces a cytogenetic response in blast crisis or interferon failure chronic myeloid leukemia patients with e19a2 BCR-ABL transcripts
Imatinib induces a cytogenetic response in blast crisis or interferon failure chronic myeloid leukemia patients with e19a2 BCR… 
1998
1998
A novel factor V null mutation detected in a thrombophilic patient with pseudo-homozygous APC resistance and in an asymptomatic unrelated subject.
To The Editor: Pseudo-homozygous APC resistance[1][1] is defined by finding the heterozygous factor V (FV) R506Q substitution… 
1988
1988
Phorbol ester and B cell-stimulatory factor synergize to induce B-chronic lymphocytic leukemia cells to simultaneous immunoglobulin secretion and DNA synthesis.
This paper discusses the response of two B cell-type chronic lymphocytic leukemia (B-CLL) clones, 173 and 183, to the phorbol… 
1985
1985
An animal model of haemolytic--uraemic syndrome in shigellosis: lipopolysaccharides of Shigella dysenteriae I and S. flexneri produce leucocyte-mediated renal cortical necrosis in rabbits.
To develop an animal model of the haemolytic-uraemic syndrome during shigellosis, rabbits were injected with lipopolysaccharides… 
1983
1983
Determination of busulfan in plasma by GC-MS with selected-ion monitoring.
A GC-MS technique with selected-ion monitoring is described for the determination of busulfan in plasma. Busulfan is extracted… 
1982
1982
Biliprotein in adult icteric serum--demonstrated by extension of the alkaline methanolysis procedure.
We confirmed that the alkaline methanolysis procedure of Blanckaert (Biochem. J. 185: 115-128, 1980) converts the sugar… 
1967
1967
"Selective" pituitary insufficiency secondary to busulfan.
Excerpt Bone marrow suppression is undoubtedly the most important and common complication of busulfan therapy. However, other… 
1963
1963
Effects of alkylating agents on spermatogenesis in the rabbit.
Serial sperm counts have been made in rabbits treated with alkylating agents. After single injections of Busulphan, Tretamine and… 
Highly Cited
1961
Highly Cited
1961
Antifertility substances and their assessment in the male rodent.
The antifertility effects of simple alkane sulphonic esters have been examined in the male rat by a combination of serial mating…