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Immunosuppressive Agents

Known as: immunosuppressive, Immunosuppressives, [IM600] IMMUNE SUPPRESSANTS 
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The mammalian target of rapamycin (mTOR) kinase is the catalytic subunit of two functionally distinct complexes, mTORC1 and… Expand
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Highly Cited
2004
Highly Cited
2004
The mammalian TOR (mTOR) pathway integrates nutrient- and growth factor-derived signals to regulate growth, the process whereby… Expand
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Review
2004
Review
2004
Adaptive immunity depends on T-cell exit from the thymus and T and B cells travelling between secondary lymphoid organs to survey… Expand
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Review
2004
Review
2004
  • P. Halloran
  • The New England journal of medicine
  • 2004
  • Corpus ID: 34192635
Suppression of allograft rejection is central to successful organ transplantation; thus, immunosuppressive agents are crucial for… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Treatment with infliximab, a chimeric monoclonal IgG1 antibody against tumor necrosis factor, can result in the… Expand
Review
2003
Review
2003
SUMMARY Endophytic microorganisms are to be found in virtually every plant on earth. These organisms reside in the living tissues… Expand
Highly Cited
1998
Highly Cited
1998
Nutritional deprivation suppresses immune function. The cloning of the obese gene and identification of its protein product… Expand
Highly Cited
1997
Highly Cited
1997
Apoptotic cell death is important in the development and homeostasis of multicellular organisms and is a highly controlled means… Expand
Highly Cited
1991
Highly Cited
1991
Although the immediate receptors (immunophilins) of the immunosuppressants cyclosporin A (CsA) and FK506 are distinct, their… Expand
Review
1991
Review
1991
Cyclosporin A, FK506, and rapamycin are inhibitors of specific signal transduction pathways that lead to T lymphocyte activation… Expand